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Cefazolin - Europe PMC

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Last Updated: 10 September 2022

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An assessment of physical properties and the viability of osteoblast-like cells of cefazolin-impregnated calcium sulfate bone-void filler.

However, antibiotic additions to calcium sulfate cement can alter the appearance of the product. In addition, high-dose antibiotics may also be harmful to bony tissues. Cefazolin in varying weight ratios was added to calcium sulfate samples and characterized in vitro, according to the manufacturer. The results showed that cefazolin improved the hydration response and extended the initial setting times of calcium sulfate bone cement, as shown by the study. The cefazolin additive resulted in the decline of peak intensity related to calcium sulfate dihydrate, which indicates incomplete phase conversion of calcium sulfate hemihydrate as a result of incomplete phase conversion of calcium sulfate hemihydrate, according to the X-ray diffractometer. In addition, scanning electron microscope examination revealed cefazolin, which changed the morphology and size of the crystals dramatically. Compared to those in uploaded samples, a relatively higher amount of cefazolin additive led to a faster breakdown and a reduced compressive strength of calcium sulfate.

Source link: https://europepmc.org/article/MED/36053824


Simple determination of urine cefazolin concentration in pediatric patients with urinary tract infections using high-performance liquid chromatography.

This research was intended to establish urinary concentrations of a 1st generation cephem antibiotic in pediatric patients with urinary tract infections in pediatric patients with urinary tract infections in pediatric patients with urinary tract infections. Ury cefazolin serum concentration in a pediatric patient with a UTI was 1,476. 6 u03bc/mL, which was more than 700-fold higher than the minimum inhibitory concentration of cefazolin. bcg/mL As a medical drug testing of cefazolin, the developed strategy is applicable to the determination of appropriate use for UTIs treatment as a therapeutic drug monitoring.

Source link: https://europepmc.org/article/MED/36049091

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions