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Caudate Nucleus - Crossref

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Last Updated: 10 January 2023

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Intraventricular lesions in tuberous sclerosis complex: a possible association with the caudate nucleus

Object Tuberous sclerosis Complex can be present with three specific intracranial pathologic entities: cortical tubers, subependymal nodules, and subependymal giant cell astrocytomas. In a large population of TSC patients, the authors investigated the incidence and expansion of intraventricular lesions. Methods The authors retrospectively reviewed brain MRI scans of TSC patients for whom at least one electronically stored cranial MRI study was available, in anticipation of institutional review board protocol approval. Three tumors along the CTG had 34 lesions, of which 23 were stable in size and 11 increased, among other patients with more than four years of follow-up. In 1 patient, the earliest correlation of SENs and the caudate nucleus was shown by a seven-Tesla MRI. Conclusions Intraventricular lesions in TSC patients are present throughout the lateral ventricular wall. Knowing why these lesions arise in relation to the caudate nucleus may provide insights into therapy.

Source link: https://doi.org/10.3171/2011.12.peds11418


TRPV4 mRNA is elevated in the caudate nucleus with NPH but not in Alzheimer’s disease

These two conditions are closely related, and it is easy to misdiagnose these two diseases. We analyzed human caudate nucleus tissue samples for the presence of transient receptor potential cation channel subfamily V4 member 4 and amyloid precursor protein. The mutability of TRPV4 and other genes in mice, rats, and humans was determined by comparing nucleotides of six genes of concern and one house keeping gene with two factors associated with high mutation rate: 1 nearness to telomeres or 2 high adenine and thymine A + T content using the genome data viewer. According to our findings, TRPV4 gene size and mutability are conserved in three species, indicating that TRPV4 is a potential link in chronic hydrocephalus in elderly humans > 65 years and laboratory rodents at similar ages.

Source link: https://doi.org/10.3389/fgene.2022.936151


Comparison of accuracy between FSL’s FIRST and Freesurfer for caudate nucleus and putamen segmentation

Abstract Abstract: Although many algorithms have been developed to automatically delineate subcortical gray matter structures from MR images, the reliability of these algorithms has not been thoroughly investigated. The isotropic resolution 1 mm 3 isotropic resolution was obtained for thirty healthy subjects. The following statistics were investigated: Dice coefficient, percentage volume difference, absolute volume difference, and intraclass correlation coefficient for consistency and absolute agreement were all tested using manual labels as a reference standard. FIRST and Freesurfer were more alike for caudate segmentation. When compared to manual tracing, Freesurfer and FIRST are not similar.

Source link: https://doi.org/10.1038/s41598-017-02584-5


Local structural-functional connectivity decoupling of caudate nucleus in infantile esotropia

In patients with infantile esotropia, abnormal brain structural and functional characteristics were found. In IE patients and those of healthy controls, the SC-FC coupling for global connectome, short connectome, and long connectome was investigated. In IE patients, the Pearson correlation between coupling measures and strabismus degree was examined, although the effect of age was also investigated by hierarchical regression analysis. In left-caudate nucleus in IE patients, SC-FC coupling scores for short connections was reduced significantly, although no brain regions had changed coupling metrics for global connections or long connections, according to the authors. In IE patients, the age-related regulatory effect on coupling-degree association was distinguishing between brain regions involved in visual processing and cognition-related brain regions.

Source link: https://doi.org/10.3389/fnins.2022.1098735


Neural oscillations in the primate caudate nucleus correlate with different preparatory states for temporal production

The number of visually-evoked potentials in monkeys' caudate nucleus work at three different times in a time production task differed, depending on the circumstances. These results show that altering network state in the cortico-basal ganglia pathways indexed by the low frequency oscillations could be critical in the regulation of signal transmission and subsequent timing behavior.

Source link: https://doi.org/10.1038/s42003-019-0345-2


Locomotion and eating behavior changes in Yucatan minipigs after unilateral radio-induced ablation of the caudate nucleus

Selective Cd lesions can be found in neurological disorders. However, little is known about the behavioural changes during progressive Cd ablation, although it is also unknown. The gradual ablation of a brain region of limited adverse effects in surrounding normal tissue is possible by modern stereotactic radiosurgery techniques. This may be of utmost importance for the analysis of the modified behavioral functions as a result of the brain structures' impairment. We investigated the effects of unilateral radio-ablation of the right Cd on Yucatan minipigs using hypofractionated stereotactic radiotherapy and synchrotron microbeam radiation, one year after irradiation. In three fractions, the right Cd was irradiated to a minimal dose of 35. 5 Gy delivered in three fractions. i. e. , MRI-based morphological brain stability and behavioral functions, i. e. We concluded that early behavioral changes related to eating habits are important indicators for the early detection of Cd-related neurological disorders.

Source link: https://doi.org/10.1038/s41598-019-53518-2


Control of response interference: caudate nucleus contributes to selective inhibition

Abstract: While the role of cortical areas in cognitive control processes is well known, the role of subtical structures in response control processes is still unclear. Clusters were found in the right anterior cingulate cortex, the right posterior insula, and the caudate nucleus bilaterally in contrast to incongruent trials. Our findings support the belief that response inhibition by cognitive mechanisms is promoted by a fronto-striatal circuitry, with a role for the selective inhibition of interfering response tendencies.

Source link: https://doi.org/10.1038/s41598-020-77744-1


Altered functional connectivity of the right caudate nucleus in chronic migraine: a resting-state fMRI study

Abstract Background The definitive pathogenic causes of chronic migraine are not clear. Nevertheless, data regarding the role played by CN in CM patients is limited, but there is also limited data. We also compared the subgroups of CM and Pearson'u2019s correlation analyses between FC values and the clinical characteristics of CM patients. Results: The right CN and five clusters' FC values were higher in CM patients than in HCs, according to the results. In the CM patients, improved FC values were seen between the bilateral precuneus, left anterior cingulate gyrus, right middle cingulate cortex, right lingual gyrus, right middle cingulate cortex, right linguistic gyrus, right lingual gyrus, and right CN were all present. There were no significant differences between CM patients with and without MOH, males and females, and females. In addition, right CN-related FC scores in the left calcarine cortex and right lingual gyrus were positively correlated with headache scores in the visual analogue scale.

Source link: https://doi.org/10.1186/s10194-022-01506-9


Volumetric reduction in caudate nucleus following stereotactic lesions of anterior cingulate cortex in humans: a morphometric magnetic resonance imaging study

Following anterior cingulate lesioning in nine patients, morphometric magnetic resonance imaging techniques were used to determine volume reductions in subcortical regions. Magnetic resonance imaging results obtained before and 9 u00b1 6 months after anterior cingulotomy were subjected to segmentation and subcortical parcellation, according to magnetic resonance imaging results. In addition, the magnitude of volume reduction in the caudate body was highly correlated with total lesion volume. These findings, taken together, indicate substantial connectivity between a region of anterior cingulate cortex lesioned during cingulation and the caudate body.

Source link: https://doi.org/10.3171/jns.2000.93.6.1019


Chemogenetic disconnection between the orbitofrontal cortex and the rostromedial caudate nucleus disrupts motivational control of goal-directed action

We specifically activated Designer Receptors in two male macaque monkeys using the chemogenetic technologies of Designer Receptors exclusively activated by Designer Drugs with a cross-inactivation scheme, causing us to crash and restore interactions between the OFC and rmCD. These findings show that the interaction between the OFC and the rmCD is necessary for motivational control of action on the basis of both perceived reward value and internal motivation. We conclude that the link between the orbitofrontal cortex and the rostromedial nucleus is crucial for monkey motivational control. This finding expands our understanding of how the primate brain regulates motivation and behavior, as well as providing more insight into conditions such as obsessive-compulsive disorder, in which altered connectivity between the orbitofrontal cortex and the striatum has been implicated.

Source link: https://doi.org/10.1101/2022.04.22.489147

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions