Advanced searches left 3/3

Cationic Liposomes - Europe PMC

Summarized by Plex Scholar
Last Updated: 02 October 2022

* If you want to update the article please login/register

Cationic liposomes as promising vehicles forTimolol/Brimonidine combination ocular delivery in glaucoma: Formulation development and in vitro/in vivo evaluation

Among the combination drugs used in glaucoma therapy, there is a specific mixture of Timolol maleate and Brimonidine tartrate. The results showed that the liposomal formulation significantly reduced the intraocular pressure relative to the original aqueous solution's simple formulation, and both formulations were able to dramatically reduce the intraocular pressure relative to the control group. After 90 h, it appears that the chosen liposomal formulation has a therapeutic role in lowering intraocular pressure, prevents, and intraocular pressure return to normal value. It also appears that the proposed liposomal formulation by Thin Layer Hydration may have a therapeutic effect in reducing intraocular pressure, preventive action, and intraocular pressure return to normal values.

Source link: https://europepmc.org/article/PPR/PPR546785


Clinical evaluation of the brightening effect of chitosan-based cationic liposomes.

Background Cationic liposomes can improve the permeability of medications in 3-D skin. Aims, This study looked at the change in skin tone, melanin, and melasma after treatment with niacinamide-infused chitosan cationic liposomes. Methods A skin brightening agent, niacinamide, was developed into cationic liposomes to promote percutaneous absorption and was clinically tested in 21 Korean female subjects. After mixing an oil phase with lecithin and cholesterol and a squeous phase containing niacinamide and chitosan, a high-pressure homogenizer was used to produce Cationic liposomes. Conclusions According to this, chitosan liposomes heightened the percutaneous absorption of niacinamide and improved the skin's appearance.

Source link: https://europepmc.org/article/MED/36052771

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

Source Recommendations

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions