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Genetics therapy is considered useful method for reliable cancer treatment. Nevertheless, the design of reliable delivery systems that can deliver gene materials such as siRNA especially to the tumour tissues plays an essential role in cancer cells therapy. Cyclic RGD was selected based on speculation that cyclic RGD would properly transfer anti-signal transducer and activator of transcription 3 siRNA into cancer malignancy cell via integrin receptors. Whole-body imaging verified the a lot more considerable tumor buildup of targeted liposomes in B16F10 melanoma xenograft tumour-bearing mice. C-RGD peptide changed liposome recommends a promising option for particular siRNA delivery into melanoma cells.
Source link: https://europepmc.org/article/MED/34482780
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