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Cataracts surgery - ClinicalTrials.gov

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Last Updated: 10 August 2022

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Ocular Clarity After Cataract Surgery With Two Different Phacoemulsification Systems

The lens is surgically extracted after cataract surgery, after which a clear artificial intraocular lens is implanted. Patients are relying on others more than ever, and it is critical that they recover functional vision as soon as possible after surgery. The most notable differences between phacoemulsification techniques, the way the needle oscillates, and the system's fluid dynamics are the key differences between phacoemulsification methods.

Source link: https://clinicaltrials.gov/ct2/show/NCT05489198


Visual Function and Patient Satisfaction in Glaucoma or Ocular Hypertensive Patients Undergoing Simultaneous Cataract Surgery and i-Stent Implantation

The aim of this research is to detail visual function and patient satisfaction in patients with glaucoma and ocular hypertension undergoing cataract surgery with bilateral implantation of an extended depth of focus IOL, the Vivity IOL. The analysis also looks at whether there are differences in the speed of vision improvement between patients undergoing isolated cataract surgery and patients undergoing simultaneous i-Stent placement.

Source link: https://clinicaltrials.gov/ct2/show/NCT05392738


Safety and Effectiveness of Single-dose Subconjunctival Triamcinolone Compared to Topical Prednisolone Eye Drops in Manual Small Incision Cataract Surgery

Eye drops administered following cataract surgery for the prevention of post-operative inflammation of post-operative inflammation have many drawbacks, including cost and poor medication use. This is a randomized control trial comparing the results of single-dose subcutaneous triamcinolone administration at the time of surgery to the commonly 4-week taper of topical prednisolone drops following manual small incision cataract surgery in Guatemala. Patients will be screened at post-operative weeks 6 and 12 for the key outcome variables of intraocular pressure and best corrected visual acuity. Data on the presence and quantity of corneal edema, anterior chamber inflammation, and the formation of macular edema will also be obtained.

Source link: https://clinicaltrials.gov/ct2/show/NCT05248139


Impact of Music Added to the Usual Treatment on the Anxiety of Patients Undergoing Outpatient Cataract Surgery With Topical Anesthesia: Randomized Controlled Trial

Most patients undergoing cataract surgery benefit from a short outpatient course with topical local anesthesia. Often being in a waiting room with other patients can exacerbate this anxiety. Patient anxiety may rise blood pressure, possibly leading to the prescription of nicardipine to encourage surgery to be carried out. Patients with anxiety are the only ones with anxiety in lieu of anxiolytics' administration. In several studies, the effects of music on preoperative anxiety has been studied, and there has been a dramatic decrease in anxiety before surgery. MusicCareU00ae is a 'digital therapy'' based on the principles of hypnoanalgesia, which has been studied in the treatment of patients with a variety of pathologies and has shown relative success. We would like to investigate the effect of offering the MusicCare u00ae listening device on patients' fear of absence in the context of cataract surgery with topical anesthesia.

Source link: https://clinicaltrials.gov/ct2/show/NCT04781231


Evaluation of the Efficacy of LipiFlow Thermal Pulsation Treatment Performed Before Cataract Surgery in Patients Affected by Meibomian Gland Dysfunction in Reducing Postoperative Dry Eye Disease

Dry Eye Disease is a disease of the ocular surface that can be related to a variety of conditions, including cataract surgery. In addition, it is a risk factor for DED exacerbation after cataract surgery, which can be present in about 40% of cases. Hence, the ocular surface of the ocular surface prior to cataract surgery is critical to ensure improved post-operative ease and a more consistent refractive result. The introduction of LipiFlow thermal pulsation therapy is a controlled method of squeezing the obstructed Meibomian glands by applying heat to the upper and lower eyelids while simultaneously applying pulsatile pressure to the eyelid skin surfaces. The aim of our study will be to determine the effect of preoperative LipiFlow therapy in patients with age-related cataracts and mild to moderate MGD in lowering postoperative DED.

Source link: https://clinicaltrials.gov/ct2/show/NCT05062564


Comparison of Corneal Endothelial Cell Loss and Cumulative Dissipated Energy Between Femtosecond Laser Assisted Cataract Surgery and Standard Phacoemulsification With the Active Sentry or OZil Handpiece

Femtosecond Laser Assisted Cataract Surgery has recently emerged as a new common surgical treatment amongst ophthalmologists. The femtosecond laser is a new device that is being used for cataract surgery. The LenSx laser is one of the most commonly used LFS for cataract surgery and is part of the CENTURION Vision system. The Frequency Domain - Optical Coherence Tomography optical imaging system provides a high-resolution, real-time visualization of ocular structures and their dimensions. This handpiece improved phaco efficiency by minimizing core fragment repulsion, collateral tissue damage, and the amount of electricity required. However, a new generation of handpieces called Active Sentry, which is part of the latest Active Fluidics, has the capability of measuring the pressure inside the eye in real time and adjusting it to prevent significant variations. The number of endothelial cell death as well as the amount of energy required to fragment the lens are both important factors in determining collateral damage caused by cataract surgery is variable. When compared to standard phaco, few studies have found an increase in ECL and CDE in patients undergoing FLACS as well as CDE, but long-term results were not conclusive. In addition, the investigators hypothesize that patients undergoing standard phacoemulsification with the Active Sentry handpiece will have less corneal endothelial cell damage and require less CDE than patients undergoing standard phacoemulsification with OZil.

Source link: https://clinicaltrials.gov/ct2/show/NCT05119270


Quality of Life and Uncorrected Binocular Visual Acuity (UBVA) Evaluation in Patients Undergoing Cataract Surgery Using 4 Different Types of Lens Implant Combinations: a Multicenter, Prospective, Comparative and Randomized Study

Cataract surgery by ultrasonic phacoemulsification is France's most common surgical procedure. This is a presbyopia compensation scheme that aims to cause one eye's nearsighted myopization of one eye for nearsighted vision with one eye's other eye being aimed at distance vision. Patients are also very active on a professional level, so choosing the intraocular implant to use is a difficult challenge. In addition, there is a lack of scientific consensus regarding implants, during a surgical treatment of cataract lenses by phakoexeresis, for otherwise healthy eyes, and in a field where aiming to no longer wear glasses postoperatively. Different studies have been published comparing the bilateral implantation of different types of multifocal implants with each other, but there is no research into mixed batches of "mix - match" implants.

Source link: https://clinicaltrials.gov/ct2/show/NCT05376917

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions