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Frequent postoperative drop usage is a burden for elderly or indigent patients who have a difficult time in following standard postoperative regimens, contributing to elevated incidences of postoperative drop noncompliance and complications. Patients undergoing cataract surgery at Zuckerberg San Francisco General Hospital, a safety-net county hospital, are now on a standard regimen of several different eye drops as part of routine postoperative recovery from cataract surgery and prophylaxis against the most unusual of all surgical complications: endophthalmitis and cystoid macular edema. According to a new survey of clinic results, approximately 40% of patients undergoing cataract surgery at ZSFG are non-adherent or only partially adherent to postoperative eye drops, memory or understanding the drop rate, and keeping physical records of multiple bottles without losing them or having them stolen, according to a few reasons, including difficulty instilling drops, remembering or understanding the drop regimen, or knowing they were stolen. With increasing numbers of eye drops and increased frequency and complexity of drop regimens, the prevalence of comorbid ocular pathologies requiring separate chronic drop therapy among this group is high in this region. According to new retrospective reviews, single injections of cefuroxime and triamcinolone acetonide in the eye at the time of surgery is safe and noninferior to standard drop protocols in preventing postoperative complications among non-indigent patients. Given the high rate of patient non-adherence to the recommended postoperative care, the investigators suggest that the therapy may be superior to the current standard procedure for preventing postoperative complications in this population.
Source link: https://clinicaltrials.gov/ct2/show/NCT05157113
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