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To determine the effectiveness and difficulties of a new type of minimally invasive femtosecond laser assisted cataract surgery involving pars plana vitrectomy with two-step anesthesia in the treatment of several common fundus disorders, including retinal detachment, epithelicular membrane, macular hole, and vitreous opacity, complicated with cataract, it is necessary to determine opacity.
Source link: https://clinicaltrials.gov/ct2/show/NCT05588037
Cataract surgery by ultrasonic phacoemulsification is France's most common surgical procedure. This is a presbyopia compensation scheme that aims to cause a slight myopization of one eye for near vision; the other eye being intended for distance vision. However, patient expectations in terms of comfort with vision and independence from glasses are increasing, and patients are becoming increasingly aware of the existence of multifocal implants. Moreover, there is also a lack of scientific evidence related to the choice of implants, during a surgical treatment of cataract lenses by phakoexeresis, for otherwise healthy eyes, and in a situation where patients must no longer wear glasses postoperatively. Different studies have been published comparing the simultaneous implant of various types of multifocal implants with each other, but there is no research into mixed batches of "mix - match" implants.
Source link: https://clinicaltrials.gov/ct2/show/NCT05376917
Benzalkonium chloride is the most common eye drop preservative and has been associated with a variety of ocular adverse reactions, including dry eye and ocular surface inflammation. Moreover, anterior chamber inflammation was reported in two clinical trials comparing the effects of BAK-containing and preservative-free eye drops, and anterior chamber inflammation in response to BAK after 1 month of exposure. Finally, there are some studies that suggest that BAK may also play a role in macular edema formation. Preservative-free eye drops have been produced in the last decade, resulting in preservative-free alternatives for nearly all of the eye medications. The aim of this project is to determine whether omitting preservatives from postoperative topical therapy after cataract surgery may reduce the incidence of cystoid macular edema, intra-ocular inflammation, and the incidence of cystoid macular edema. In addition, ocular microbiome research has been added to our study due to its well-known association with ocular immunity. Although the ocular surface is continuously colonized by a commensal microbial species, the healthy ocular surface is not in an inflammatory state. Our ocular microbiome research scientist is affiliated with the University of Ghent's department of biochemistry and microbiology.
Source link: https://clinicaltrials.gov/ct2/show/NCT04050644
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