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Cataract Glaucoma - Europe PMC

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Last Updated: 08 August 2022

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Comparison of minimally invasive glaucoma surgery with trabecular micro-bypass stent and microhook ab interno trabeculotomy performed in conjunction with cataract surgery.

Aim: To evaluate the effectuality and safety of cataract surgery, as well as ab initio trabeculotomy by the microhook or a single iStent trabecular bypass implantation in eyes with cataract and mild-to-moderate glaucoma, use the u01ae trabeculotomy by the microhook or a single iStent u00ae trabecular bypass implantation in eyes with cataract and mild-toma Methods This review included patients with moderate to moderate open angle glaucoma with visually impaired cataracts who used two or more ophthalmic antiglaucoma drugs between 60 and 90 years of age. According to the Humphrey field analyzer, patients underwent u00b5LOT-phaco in the eye with lower mean deviation, but iStent-phaco was carried out on the other eye. The iStent eyes had 13. 6 mm Hg in the u00b5LOT' eyes and 13. 6 mm Hg, respectively, at 12 mm Hg, indicating a 17. 8% and 17. 2% decrease, respectively. ACF was 9. 6 pc/ms preoperatively and returned to normal by 7d postoperatively, implying that postoperative inflammation was less present in the iStent eyes.

Source link: https://europepmc.org/article/MED/35919323


A case report about infective endophthalmitis caused by Ochrobactrum anthropic after glaucoma and cataract surgery

Background: The aim of this investigation was to report unusual case of infective endophthalmitis one week after Glaucoma and cataract surgery in her left eye. bacterial endophthalmitis was successfully treated after two times of intravitreal and anterior chamber injections of moxifloxacin and imipenem, as well as intravenous and ocular medications.

Source link: https://europepmc.org/article/PPR/PPR513938


Aqueous Humor Cytokine Response in the Contralateral Eye after First-Eye Cataract Surgery in Patients with Primary Angle-Closure Glaucoma, High Myopia or Type 2 Diabetes Mellitus.

Background Bilateral sequential cataract surgery within a short time is getting more popular due to the efficiency and safety of modern cataract surgery. It has been suggested that the first surgical eye can influence the contralateral eye. This research looked at the cytokines involved in pre-existing ocular or systemic disease, as well as the inflammatory biomarkers in reaction to topical stimuli by analyzing the cytokine profile of aqueous humor from cataract patients without these morbidities as control and with type 2 diabetes mellitus, primary angle-closure glaucoma, or high myopia in each eye at the beginning of first and second eye cataract surgery. In PACG and HM, the basic fibroblast growth factor was more prevalent in PACG and HM, while in PACG, monocyte chemoattractant protein-1 and interferon gamma-induced protein 10 were decreased, while monocyte chemoattractant protein-1 and interferon induced protein 10 were significantly higher. In the AH of contralateral eyes following first-eye surgery between the four groups, there was an overlap of 5 altered cytokines in the AH of contralateral eyes relative to baseline. Patients with pre-existing ocular or systemic diseases have some degree of inflammation in their eyes before surgery and in the contralateral eye after the first eye cataract surgery, which may be unusual due to the patient's morbid conditions. In patients with type 2 DM prior to surgery, inflammation was more evident in patients with type 2 DM. Compared to controls and DM patients, PACG and HM patients had greater intraocular inflammation responses to topical stimuli.

Source link: https://europepmc.org/article/MED/35866408


Case Report: Combined Cataract Surgery and Minimally Invasive Glaucoma Surgery Provide an Alternative Treatment Approach for Lowe Syndrome.

The boy underwent lensectomy for congenital cataracts in his right eye, and lensectomy with a 360°u00b0 suture trabeculotomy to eliminate the clouded lens and monitor IOP of the left eye. Lowe syndrome is a rare multisystemic disorder that is detected by clinical manifestation and genetic testing. For patients in Lowe syndrome, we recommend combined cataract surgery and minimally invasive glaucoma surgery as a safe, effective, and cost-effective way to resolve congenital cataract and glaucoma.

Source link: https://europepmc.org/article/MED/35847784


Association of Diabetes Medication With Open-Angle Glaucoma, Age-Related Macular Degeneration, and Cataract in the Rotterdam Study.

In a large cohort study, the aim was to determine the connection between diabetes medication and common eye diseases OAG, AMD, and cataract, as well as quantifying their lifetime risks. Metformin therapy for T2D was correlated with a reduced risk of OAG. AMD-reducing diabetes drugs have been shown to have a reduced risk of AMD. Individuals taking metformin were less likely to experience OAG than those without T2D; however, the lifetime risk of AMD was lower among those taking other diabetes drugs. Conclusions and relevance of this cohort report show that although diabetes was clearly associated with cataracts, diabetes therapy was not. Metformin therapy led to a reduced risk of OAG, and other diabetes medications were associated with a reduced risk of AMD.

Source link: https://europepmc.org/article/MED/35587864


Combined phacoviscocanalostomy versus phacoemulsification alone in patients with coexisting cataract and mild-to-moderate open-angle glaucoma; a randomized-controlled trial.

Concomitant cataract and glaucoma management is subjected to the stage of glaucoma and the patient's health. We collected 89 eyes from 89 patients with mild-to-moderate primary OAG or pseudoexfoliative glaucoma with visually significant age-related cataracts. Results After the 1st and 3rd months, the mean IOP decreased significantly in the phaco-visco group relative to the phaco group, but it was not statistically significant at 6th and 12th months. Conclusions Although both phacoemulsification and phacoviscocanalostomy procedures should be considered for patients with mild-to-moderate OAG, we found improved success rates using phacoemulsification alone and phacoviscocanalostomy drugs. Therefore, if the surgeon is an expert at this procedure, this non-penetrating therapy can be used in patients with visually impaired cataracts and earlier stages of OAG, especially in patients with PEXG.

Source link: https://europepmc.org/article/MED/35752716


Intraoperative malignant glaucoma during femtosecond laser-assisted cataract surgery: A case report.

Rationale Femtosecond laser-assisted cataract surgery has gained traction among ophthalmologists as a novel surgical procedure. Patient concerns A 66-year-old woman was greeted with reports of blurred vision in the right eye and a foreign body sensation in both eyes. The intraocular pressure was 20 mmHg in the right eye and 17 mmHg in the left eye without any topical anti-glaucoma drugs. The cornea with a defect in the punctate overlying epithelium was revealed, according to a transparent cornea with a crack in the punctate overlying epithelium; the central anterior chamber depth was shallow; the pupil was normal; and the lens was mainly cortical opacified. We explore the occurrence of MG after FLACS and show that miosis and bubble formation after FLACS may be risk factors for MG during FLACS.

Source link: https://europepmc.org/article/MED/35758354


Quantitative OCT Angiography Assessment of the Effect of Peribulbar Anesthesia on Retinal Microvasculature in Primary Open-Angle Glaucoma Patients Undergoing Cataract Surgery.

Using OCT Angiography, we investigated the effect of peribulbar anesthesia on retinal microvasculature in primary open-angle glaucoma patients undergoing cataract surgery. Patients with no prior glaucoma were excluded from Group I, while Group II included patients who had been previously diagnosed as POAG with monitored IOP. Each participant received 6 mL of peribulbar anesthetic injection of 4 mL lidocaine 2% containing 150 IU hyaluronidase and 2 mL bupivacaine 0. 5%. Results Median percent change in DCP post-injection was significantly higher in group II than in group I. In addition, DCP total density median percent change post-injection in group II was much higher in group II than in group I. The FAZ diameter median percentage change post-injection was higher in group II than in group I. The total vessel density and radial peripapillary capillary network density post-injection median percentage change in group II and respectively were much higher in group II and respectively than in group I and respectively.

Source link: https://europepmc.org/article/MED/35757020


iStent inject ® and cataract surgery for mild-to-moderate primary open angle glaucoma in Japan: a cost-utility analysis.

From a public payer's perspective, Aim To determine the cost-utility of iStent injection versus cataract surgery alone in patients with moderate to moderate primary open angle glaucoma in the Japanese setting. Results from the randomized base case study, iStent injection u00ae with cataract surgery was found to be cost-effective compared to cataract surgery alone over a lifetime horizon when using the u00a55 000 000/quality adjusted life year willingness-to-pay threshold. In the scenario analysis from a social perspective, which included caregivers, the iStent injection u00ae with cataract surgery was found to dominate cataract surgery alone, out of cataract surgery alone. Conclusions in Japan with moderate to moderate POAGs, the iStent injection u00ae with cataract surgery is a cost-effective approach over cataract surgery alone from the public payer's viewpoint and cost-saving from the societal viewpoint on patients with mild-to-moderate POAG.

Source link: https://europepmc.org/article/MED/35814897


A Multicenter Prospective Comparative Study Evaluating Cataract Surgery and Endoscopic Cyclophotocoagulation either with or without iStent inject Implantation in Brazilian Patients with Glaucoma

Purpose: In Brazilian patients with open-angle glaucoma, compare 12-month safety and effectiveness of endoscopic cyclophotocoagulation + cataract surgery + iStent injection micro-bypass implantation. Methods This prospective, multicenter, comparative case series included patients with OAG and cataract who were randomly assigned to receive hospitalization in Group 1 or Group 2 randomized study series. Mean postoperative IOP and drugs were higher in Group 1 than in Group 2; Mean postoperative IOP and medications were higher in Group 1 than Group 2.

Source link: https://europepmc.org/article/PPR/PPR504439

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

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* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions