Advanced searches left 3/3

Catalytic Subunit - Crossref

Summarized by Plex Scholar
Last Updated: 13 August 2022

* If you want to update the article please login/register

Amino-terminal processing of the catalytic subunit from Na(+)-K(+)-ATPase

We produced a site-directed antibody specific for the first nine residues of nascent alpha 1 from rat to facilitate analysis of amino-terminal structure and the cleavage process. In Escherichia coli transformed with an alpha 1/troponin fusion protein-bound virus and in insect cells infected with baculovirus full-length alpha 1 or alpha 1T, a full-length anti-VGR was discovered. This indicates that the introduced alpha 1 in these expression systems was either missing or different from that in mammals. Green monkey kidney cells transfected with alpha 1 did not show significant binding of the antibody, indicating that the introduced isoform was processed correctly. The results show that efficient co- or posttranslational processing of nascent alpha 1 is conserved among various organs within the rat, but that the necessary modification enzymes are not present in distant phyla.

Source link: https://doi.org/10.1152/ajpcell.1996.271.3.c825


Selective tonic inhibition of G-6-Pase catalytic subunit, but not G-6 -P transporter, gene expression by insulin in vivo

Comparison of the regulation of glucose-6-phosphatase catalytic subunit and glucose 6-phosphate transporter gene expression in conscious dogs in vivo and tissue culture cells in situ. In addition, cAMP increased G-6-Pase catalytic subunit expression in H4IIE cells and primary hepatocytes, but had no effect on G-6 -P transporter expression. These findings show that the relative control strengths of the G-6-Pase catalytic subunit and the G-6-P transporter in the G-6-Pase reaction are likely to vary depending on the in vivo environment.

Source link: https://doi.org/10.1152/ajpendo.2001.281.4.e713


The protein phosphatase 2A catalytic subunit StPP2Ac2b is involved in the control of potato tuber sprouting and source-sink balance in tubers and sprouts

Abstract Sprouting has a detrimental effect on the quality of frozen potato tubers. For the production of potato varieties with desired sprouting characteristics, knowing the molecular mechanisms that control this process is crucial. Many research and stress responses in plants have been linked to the serine/threonine protein phosphatase type 2A. We investigated potato tubers' sprouting behavior when expressing the catalytic subunit 2b in this report. In StPP2Ac2b-OE tubers, sprouting and initial sprout elongation is considerably delayed; however, sprout growth is spurred during the late stages of growth, owing to a high degree of branching.

Source link: https://doi.org/10.1093/jxb/erac326


Multiple roles of apolipoprotein B mRNA editing enzyme catalytic subunit 3B (APOBEC3B) in human tumors: a pan-cancer analysis

Although there have been some recent cell and animal studies indicating that expression of the gene encoding apolipoprotein B mRNA editing enzyme catalytic subunit 3B is closely related to cancer, pan-cancer analysis is still lacking. Based on the Cancer Genome Atlas, we investigated the potential carcinogenic role of APOBEC3B in 33 tumors. APOBEC3B expression and CD8+ T lymphocyte numbers were correlated in testicular germ cell tumors and invasive breast carcinomas. This is the first pan-cancer study that provides a comprehensive overview of APOBEC3B's multiple roles in various tumor types.

Source link: https://doi.org/10.1186/s12859-022-04862-0

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions