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Many people with acatalasemia have no health problems related to the disease and are diagnosed because they have affected family members. Some of the first suspected people with acatalasemia had open sores inside the mouth that resulted in the death of soft tissue. According to studies, people with acatalasemia are at a higher risk of experiencing type 2 diabetes, the most common form of diabetes. A greater number of people with acatalasemia have type 2 diabetes than in the general population, and the disease appears to be more prevalent at an earlier age.
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