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Catabolic - Astrophysics Data System

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Last Updated: 10 January 2023

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The unusual convergence of steroid catabolic pathways in Mycobacterium abscessus

The opportunistic pathogen Mycobacterium abscessus contains catabolic pathways for cholesterol and 4-androstenedione, according to our report, and that among strains of the M. abscessus complex, the two pathways diverge at a point that is unusual among steroid-degrading bacteria. M. abscessus mutants A u0394hsaD mutant did not grow in macrophages, indicating that cholesterol is not a growth substrate for intracellular bacteria.

Source link: https://ui.adsabs.harvard.edu/abs/2022PNAS..11907505C/abstract

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions