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The JMAC study, a multinational multicenter Randomized Controlled Trial, is designed to determine the effectiveness and safety of JointRepu00ae, a second-generation chitosan-based hydrogel for cartilage repair, and to determine the quality and safety of cartilage repair. A total of 185 subjects will be randomized 2:1 to either Microfracture Plus JointRep U00ae or Microfracture alone. The new tissue quality will also be measured by structurally based and blindly measured T2; the upper and lower half of the new tissue T2 test will show the degree of stratification of the new cartilaginous tissue. A semiquantitative MOCART-2 blinded review will also be carried out.
Source link: https://clinicaltrials.gov/ct2/show/NCT04840147
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