Cartilage Tissue Engineering - Crossref

Effects of Electrical Stimulation on Articular Cartilage Regeneration with a Focus on Piezoelectric Biomaterials for Articular Cartilage Tissue Repair and Engineering

These results point to the potential use of ES in cartilage repair. We review the genesis of articular cartilage injuries in this report as well as the current medical practices for treating articular cartilage injuries. In vivo, we then focusing on the use of ES in the repair of articular cartilage. We also explore the possibility of using piezoelectric materials in the process of fabricating engineering articular cartilage, undermining the numerous advances in the field of tissue engineering.

Source link: https://doi.org/10.3390/ijms24031836

Combinations of Hydrogels and Mesenchymal Stromal Cells (MSCs) for Cartilage Tissue Engineering—A Review of the Literature

Cell-based therapies have emerged as a promising alternative to cartilage defects and osteoarthritis therapy. Mesenchymal cell cells are a popular cell source due to their easy access, absorption, and chondrogenic potential mesenchymal stromal cells. We investigated the effects of added growth factors or gene transfer in MSC-laden hydrogels, focusing on chondrogenesis in MSC-laden hydrogels.

Source link: https://doi.org/10.3390/gels7040217

Hyaluronic acid and multiwalled carbon nanotubes as bioink additives for cartilage tissue engineering

In this regard, 3D bioprinting has emerged as one of the most promising new techniques, providing novel treatment options. As bioink additives, we looked closer at hyaluronic acid and multi-walled carbon nanotubes in this report. We firstly investigated the minimal concentrations that improve cell growth, enhanced cell growth, and reduced reactive oxygen species and apoptosis levels in 2D cell cultures of normal human knee articular chondrocytes and human adipose-derived mesenchymal stem cells in 2D cell cultures of human knee articular chondrocytes and human adipose-derived mesenchymal stem cells in human chondrocyte stem cells in 2D chondrocyte apoptosenchym chondr chondrocytes and chondrocytes and chondrocyte chondrocytes and human chondrocyte chondrocytes and human chondrocytes and mesenchymal stem cells chondrocytes and human chondrocytes and human adrocytes and human adrocytes In this regard, 0. 25 mg/ml of hyaluronic acid and 0. 0625 mg/ml of carbon nanotubes were chosen as the most desirable concentrations. In addition, we investigated the anti-plague activity of 2-phospho-L-ascorbic acid in carbon nanotube samples. Gene expression analysis of COL1A1, COL6A1, HIF1A, COMP, RUNX2, and POU5F1 revealed significant changes in the expression of all tested genes with a gradual decline of transcriptional activity in the majority of them.

Source link: https://doi.org/10.1038/s41598-023-27901-z

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