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Introduction/objectives The connection between serum biomarker [cartilage oligomeric matrix protein and matrix metalloproteinase-3 ] levels and medical, magnetic resonance imaging, and arthroscopic findings in anterior cruciate ligament -deficient knees without osteoarthritic changes on radiographs can be investigated. Patients with ACL injury of Kellgren–Lawrence grade 0 or 1 were accepted for the treatment. Higher serum COMP scores were correlated with older age and higher BMI, TAS score, serum MMP-3 level, WORMS, and T2 relaxation times, according to a survey conducted by the University of Higher serum COMP level. The serum COMP level was independently related to WORMS and ICRS grade, according to a multivariate analysis. Also in patients with radiographic osteoarthritic disease, the serum COMP level will help determine cartilage degeneration even in patients with cartilage degeneration. In ACL deficient knee, the core points were:: Serum COMP was correlated with WORMS and ICRS grade, according to WORMS and ICRS ratings. The serum COMP level could help in detecting cartilage degeneration, even in patients with no radiographic osteoarthritic abnormalities.
Source link: https://doi.org/10.1007/s10067-021-05800-w
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