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Carpal Tunnel - Astrophysics Data System

Summarized by Plex Scholar
Last Updated: 10 April 2022

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A genome-wide meta-analysis identifies 50 genetic loci associated with carpal tunnel syndrome

Carpal tunnel syndrome is the most common entrapment neuropathy and has a relatively unknown underlying biology. Through various functional experiments, we find that at least 22 genes mediate CTS risk and highlight the role of 19 CTS variants in the extracellular matrix's biology. In bilateral/recurrent/persistent cases than nonrecurrent/nonpersistent cases, the genetic component to the risk is higher than nonrecurrent/persistent cases, according to our results. According to our results, the extracellular matrix components of the extracellular matrix play a significant role in CTS pathogenesis.

Source link: https://ui.adsabs.harvard.edu/abs/2022NatCo..13.1598S/abstract

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions