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Introduction: A extensive neovascularization in atherosclerotic plaque has been shown to be correlated with plaque formation and instability, resulting in atherosclerotic cardiovascular events. Hypothesis: Using quantitative analysis of CEUS results, the carotid artery artery's coronary artery disease can be determined by intra-plaque neovascularization of the carotid artery, providing prognostic data in patients with coronary artery disease. Methods: This research included 206 patients with stable CAD and carotid intima-media thickness > 1. 1 mm. The degree of contrast signals detected within the carotid plaque after the intravenous injection of contrast material was quantified by determining the rise in mean gray scale level within the region of concern of the carotid plaque was quantified by measuring the change in mean gray scale level within the carotid plaque's region of concern, expressed as plaque increased intensity. According to the Multivariate Cox proportional hazards report, plaque increased intensity was a key predictor of cardiac events independent of traditional risk factors. Conclusions: The investigation of carotid plaque neovascularization using quantitative measures of CEUS may be useful for risk stratification in patients with CAD.
Source link: https://doi.org/10.1161/circ.130.suppl_2.11733
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