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Background Carotid vulnerable plaque is a significant risk factor for stroke development and recurrence. However, the relationship between risk factors relating to carotid vulnerable plaque and neuropathy following ischemic stroke or TIA is uncertain. This report investigates the use of multimodal ultrasound-based calcium plaque risk biomarkers to predict poor short-term functional outcomes following ischemic stroke or TIA. Patients were followed up 90 days after the completion of a baseline ultrasound, and patient modified neurological function scores were published after completion of a baseline ultrasound. SMI reported that 20 patients had extensive neovascularization in the carotid plaque, while 45 patients had limited neovascularization in the carotid plaque, according to SMI. The mean carotid plaque stiffness, according to SWE imaging, was 51. 49 kPa. The level of intraplaque neovascularization and plaque stiffness, according to a mRS of 2-6, were independent risk factors for a mRS of 3-6, with the degree of intraplaque neovascularization and plaque stiffness as independent risk factors for a mRS of 3-6. The HR of intraplaque neovascularization level and plaque stiffness predicted a mRS 2-6 was 3. 06 and 0. 51 respectively, with forecasts predicting a mRS 2-6 at 6. 11. Conclusions Intraplaque neovascularization level and plaque stiffness may be attributed to an elevated risk of poor short-term functional outcome in patients with acute anterior circulation ischemic strokes as a result of carotid atherosclerosis.
Source link: https://europepmc.org/article/MED/36631804
The risk assessment of carotid plaque is strongly related to ultrasound plaque echo status. However, the echo classification of carotid plaques based on ultrasound remains challenging due to the changes in plaque shape and semantics, as well as the intricate vascular environment. The results of the experiments revealed that CPTV's results are more effective than current standard tracking and classification schemes, showing that the tracking-assistance classification is a type of improvement strategy with high universality and stability in the plaque in ultrasound.
Source link: https://europepmc.org/article/MED/36630795
With the voxel-based VWV conversion, the vessel wall region was divided into small voxels, resulting in a percentage difference between corresponding voxels in the baseline and follow-up photographs. Calculating the mean u0394VVol% over the entire 3-D map for each patient was a new patient-based biomarker. Patients randomized to pomegranate juice/extract and placebo groups differed greatly from placebo/control groups, according to u0394Vol%u00af. About a third of the total number of patients needed by u0394Vu00af to establish statistical significance was less than a third of that used by the local VWT biomarker.
Source link: https://europepmc.org/article/MED/36566092
Background Stenosis has been a source of carotid endartarterectomy for four decades, but the annual stroke risk in asymptomatic carotid stenosis > 70% is less than 2%. Tomographic ultrasound is a new device that produces 3D images in seconds. In patients undergoing CEA, we checked the accuracy of measuring Carotid Plaque Volume with tUS. Method By tUS and contrast-enhanced tUS, concise patients were seen immediately before CEA by tUS and contrast-enhanced tUS. Means Mean u00b1 sd CPV in 129 endarterectomy specimens was 0. 75 percent u00b1 0. 43 cm 3 mm 3 y/b1 0. 43 cm 3, according to the u00b1 sd CPV in 129 endarterectomy specimens, a 0. 75 u00b1 0. 43 cm 3 0. 0 0. 73 cm 3. Mean b1 0. 85 cm 3 3, TUS was 0. 87 mm -u00b1 0. 51 cm 3 with fusion, and with fusion, CEtUS was 0. 75 u00b1 0. 45 cm 3 with fusion. tUS was 0. 76 mm 3 with fusion 0 b1 0. 43 cm 3 and with fusion. 43 mm 3 in tus mean u00b1 0. 49 cm 3. 49 cm 3 v tus Clinically insignificant differences between specimen volume and CPV measured by tUS, CEtUS, or fusion were statistically insignificant. If precise CPV measurements are required for study, CEtUS improves accuracy, but population screening by tUS alone would be sufficient.
Source link: https://europepmc.org/article/MED/36563846
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