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Inflammation is a component of atherosclerosis pathogenesis and is associated with an elevated risk of atherosclerotic cardiovascular disease. We investigated the cross-sectional relationship between NLR and carotid intima-media thickness in patients at moderate-to-high ASCVD risk. We analyzed the correlation between NLR, cIMT, and its 15-month change in 3341 participants from the IMT-Progression study as Predictors of VEs. Also investigated was the connection between NLR and incident VEs. CNLR was positively associated with cross-sectional ciMT testing, but not with cIMT progression. In the same vein, there were no significant differences in the hazard ratios of VEs across NLR quartiles. In primary prevention, our results do not support the role of NLR as a predictor of atherosclerosis progression and ASCVD events in subjects at moderate-to-high ASCVD risk. However, from this report, the effectiveness of NLR for patients at a different degree of ASCVD risk cannot be inferred.
Source link: https://europepmc.org/article/MED/34761838
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