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Carotid Artery Stenosis - Europe PMC

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Last Updated: 03 January 2023

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Management of extracranial carotid artery stenosis during endovascular treatment for acute ischaemic stroke: results from the MR CLEAN Registry.

Background The most suitable treatment of ipsilateral extracranial intracortid artery stenosis during endovascular therapy is uncertain. paraphrased artery stenting to determine the results of two different tactics: EVT with carotid artery stenting versus stenting stenting. Methods In this descriptive review, we included patients with an acute ischaemic stroke undergoing EVT as well as a concomitant ipsilateral extracranial stenosis of suspected clerotic origin from the Dutch Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands Registry. A deferred carotid endarterectomy or CAS was performed in 42/224 patients who underwent EVT without CAS, a deferred carotid endarterectomy or CAS was performed. Except for the increased chances of a new clot in a new geographical area in the EVT with CAS data, there were no significant differences between the two groups in any of the secondary endpoints, except for the increased chances of a new clot in a new vascular region in the EVT with CAS group. Conclusions Functional results were similar after EVT with and without CAS.

Source link: https://europepmc.org/article/MED/36572506


Hypertriglyceridemia and Atherosclerotic Carotid Artery Stenosis.

Statins are well known to prevent carotid plaque formation and increase carotid plaque instability, which is particularly useful in preventing carotid plaque formation and increasing carotid plaque permeability. In addition, statin therapy has been shown to reduce cerebrovascular events in patients with carotid artery stenosis and to improve clinical outcomes in patients undergoing revascularization procedures. On the other hand, there have been no randomized controlled trials showing that a combination of non-statin lipid-lowering drugs with statins has more beneficial results than statin monotherapy to reduce cerebrovascular events and stenosis progression in patients with carotid artery stenosis. paraphrased artery stenosis and hypertriglyceridemia. The authors also review the papers describing the correlation between hypertriglyceridemia and carotid artery stenosis.

Source link: https://europepmc.org/article/MED/36555866


Usefulness of cone-beam computed tomography to predict residual stenosis after carotid artery stenting.

Objectives The long-term stenting of carotid artery stenting may be determined by a variety of factors; nevertheless, residual stenosis is a known risk factor for in-stent restenosis. After CAS, the researchers of this paper used cone-beam computed tomography in angiosuite to investigate plaque features that could influence the appearance and quality of stent expansion. The stent configuration was determined if the stent was expanded and oval or round in shape, as well as outward or inward in orientation, according to CBCT's post-CAS CBCT. Results Oval or outward expansion is directly related to persistent stenosis, according to residual stenosis. The maximum plaque thickness, calcification barrier, and pre-CAS stenotic degree were among the variables related to > 20% residual stenosis. Conclusions The CBCT's carotid stenosis report for plaque features, particularly calcification techniques that could have an effect on the angioplasty effect, as well as the determinants and quality of stent expansion can be useful.

Source link: https://europepmc.org/article/MED/36523192


Leukocyte Count Predicts Carotid Artery Stenosis in Men with Ischemic Stroke: Sub Study of the Preventive Antibiotics in Stroke Study (PASS).

paraphrased artery stenosis patients with internal carotid artery stenosis, according to research, gender-dependent variations in the use of inflammatory markers for risk stratification of stroke patients with internal carotid artery stenosis. We investigated whether leukocytes and thrombocytes were associated with acute stroke 0–u22655 percent ICAS, and whether this was gender dependent. Patients in the Prescription Antibiotics in Stroke Study were included. PASS is a random controlled trial that randomly selected between four days of preventive ceftriaxone intravenously or standard stroke care alone. It was investigated whether ceftriaxone could enhance functional outcome three months after stroke. Methods : Patients in PASS were evaluated for the predictive value of leukocytes and thrombocytes for ICAS. Leukocytes were universally linked to ICAS u2265 percent in male patients, but not in female patients, according to a multivariate logistic regression study. Conclusions: We conclude that after acute stroke, blood leukocyte count determines ICAS in men but not in women.

Source link: https://europepmc.org/article/MED/36555901


Age and Five-Year Outcomes After Carotid Artery Stenting in Symptomatic Carotid Stenosis: A Retrospective Cohort Study.

Several clinical studies have shown that the risk of carotid artery stenting increases with age. One of the most rapid transitions to an aging society is taking place in China, however, the clinical findings of CAS in real-world China are still limited. The aim of the study was to compare the periprocedural and an extending 5-year event rates among younger and older patients treated by CAS to establish the appropriateness of CAS in elderly patients in China. There was no significant difference between the stroke and death outcomes in symptomatic patients, according to Kaplan-Meier estimates of the proportion of study participants with a primary endpoint. Conclusions : Age had no influence on the risk of stroke or death in symptomatic patients either in the short or long term. CAS is an effective therapy for older patients with cervical carotid artery stenosis, and CAS is safe for those with significant stroke or bilateral C1 stenting.

Source link: https://europepmc.org/article/MED/36476091


Increased Serum Systemic Immune-Inflammation Index is Independently Associated With Severity of Carotid Artery Stenosis.

paraphrased artery stenosis, which can be detected using carotid artery angiography. The present research examined how the systemic immune inflammation index could be used to predict the likelihood of developing carotid artery stenosis. Operating Characteristic Curve was the highest cutoff value for SII to forecast the critical CAS with 71. 2% sensitivity and 60. 1% specificity. According to our report, an rise in SIII is an independent predictor of the severity of CAS in patients undergoing CAAG.

Source link: https://europepmc.org/article/MED/36475400


The application of the nnU-Net-based automatic segmentation model in assisting carotid artery stenosis and carotid atherosclerotic plaque evaluation.

No new U-net is a recently built deep learning neural network, whose benefits in medical image segmentation have been noted recently. This paper sought to explore the benefits of the nnU-Net-based computed tomography angiography imaging system in aiding in the diagnosis of carotid artery stenosis and atherosclerotic plaque. Methods: This study retrospectively recruited 93 CAS-suspected patients who underwent head and neck CTA examination, then randomly divided them into the training group and the validation rate in a 3:1 ratio. According to 0. 975, 0. 994 0. 95, and 0. 498, respectively, the nnU-Net model in segmenting background, blood vessels, calcification plaques, and dark spots was higher than expected in the validation process: the Dice similarity coefficient value of the nnU-Net model in segmenting background, blood vessels, calcification plaques, and dark spots reached 0. 975, 0. 974 0. 795, and 0. 498. Conclusion: The automatic segmentation system based on nnU-Net offers good accuracy, scalability, and effectiveness in assisting CTA in determining CAS and carotid atherosclerotic plaques.

Source link: https://europepmc.org/article/MED/36561211


Carotid Artery Stenting for Patients with Carotid Stenosis and Contralateral Carotid Artery Occlusion: A 12-year Experience.

Objectives of Carotid artery stenting has emerged as a potential treatment for patients with additionalcranial cerebrovascular disease. In approximately 23% to 25% of patients with carotid artery stenosis, the occlusion occurs in about 2. 3 percent to 25 percent. However, the relationship of a CCO with long-term results after CAS remains unclear. After receiving CAS, we wanted to investigate the perioperative and long-term recovery and safety of patients with CCO. Methods We retrospectively gathered the records of patients with CCO treated with CAS between 2010 and 2021. The study included seventy-one consecutive patients with CCO who underwent CAS for the seventh time in a row. 2 patients died as a result of acute liver failure, car accident, cervical fracture, or unknown cause, and 4 patients died after CAS, and 6 patients died after a combined stroke at 4 and 6 months, respectively, and 6 patients died as a result of a MI. Conclusion CAS is a safe and effective treatment for patients with CCO.

Source link: https://europepmc.org/article/MED/36481673


External carotid artery to ophthalmic artery flow associated with internal carotid artery stenosis.

Purpose The point of a facial filler injection is sudden ischemic blindness, which is one of the most painful complications of facial filler injection. The aim of this research was to determine the relationship of external carotid artery anterograde flow in patients with internal carotid artery stenosis and in a control population without carotid disease. Methods The goal of this cross-sectional cohort research was based on an observation group of patients with symptomatic ICA stenosis and a control group of patients with refractory epistaxis embolization. Patients with ICA stenosis were more likely in patients with OA flow than in controls compared to controls. Conclusions Anterograde flow can be demonstrated in approximately 3% of control patients and in over 3% of patients with symptomatic carotid stenosis.

Source link: https://europepmc.org/article/MED/36469588

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions