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Carotid Artery Stenosis - Crossref

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Last Updated: 03 January 2023

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Wall Shear Stress Measurement in Carotid Artery Phantoms with Variation in Degree of Stenosis Using Plane Wave Vector Doppler

The velocity gradient along the wall was then estimated from the viscosity of a blood-mimicking fluid, which was then multiplied. With an increasing degree of stenosis, the mean WSS and maximum WSS increased. The phantom experiment showed that the mean WSS and maximum WSS increased with increasing frequency. The simulation and experiment results provide the required validation data to support WSS measurements in patients using the PW vector Doppler method.

Source link: https://doi.org/10.3390/app13010617


Use of transcarotid artery revascularization for mechanical thrombectomy and treatment of symptomatic high-grade carotid artery stenosis associated with free-floating thrombus: illustrative case

paraphrased stenosis patients with moderate to severe onset of symptomatic ICA stenosis, carotid revascularization is often recommended within two weeks of symptom onset, but some doctors maintain that early surgery with carotid endarterectomy or carotid stent may be a greater risk of stroke in patients with FFT. This paper reviewed the use of TCAR for direct mechanical thrombectomy and carotid stent placement for a patient with 80% right ICA stenosis, as well as a large FFT extending into the bulb and the external carotid artery.

Source link: https://doi.org/10.3171/case21553


Contribution of Current Comorbid Conditions to Carotid Artery Stenosis in Patients Undergoing Coronary Artery Bypass and Stroke Distribution in Carotid Artery Stenosis Groups

Objective: This study was designed to contribute to the issue of u201d and preoperative CAS by examining comorbid diseases in patients undergoing coronary artery bypass graft surgery and investigating the effects of carotid stenosis levels on postoperative stroke. Method: A total of 921 patients who underwent cardiac surgery retrospectively were examined between 2011 and 2015. Patients aged 60 and over who underwent preoperative carotid Doppler examination were analyzed. The prevalence of PAH + DM and an age older than 65 years was 55% in the decision tree analysis, with a rate of 50% and above CAS in the presence of PAH+ DM and an age older than 65 years. In the 0--29% group, 2. 8 percent in the 30-49% group, 4. 6 percent in the 50-60 percent group, and 11. 1% in the 70-99% group, with 2. 1% in the 0-29% group, 2. 1% in the 30-40 percent group, 4. 9 percent in the 59% group, and 11. 1% in the 70-99% group. In ten patients who underwent carotid endarterectomy, Postoperative CVA was not present. In six patients with 50% or more stenosis who did not undergo CE, postoperative CVA was the most common disease. Conclusion: The association of advanced age, PAD, DM, male gender, COPD, LMCAD, and hypertension risk factors should be considered in the preoperative analysis of CAS in patients undergoing CABG. Large populations are required to investigate the effects of aortic atherosclerosis load, surgical intervention, and bilateral CAS presence on stroke in patients with high CAS and postoperative CVA.

Source link: https://doi.org/10.1532/hsf.3945


The Clinical Significance of Lncrna GAS5 And Mir-222-3p in Carotid Artery Stenosis

Background: The stenosis of Carotid artery stenosis is the most common cause of cerebral infarction and brain death. In this research, the clinical value of lncRNA GAS5 and miR-222-3p in the diagnosis and prognosis of CAS was evaluated to find novel CAS biomarkers. PCR revealed that the expression of GAS5 and miR-222-3p in study subjects was determined by PCR. Results: In CAS patients, a significant correlation between their expression levels in CAS was discovered, with reduced expression of GAS5 and elevated expression of miR-222-3p in comparison to the healthy controls. CAS patients may be distinguished from the healthy controls by their high sensitivity and specificity. The GAS5 downregulation and miR222-3p upregulation may lead to poor CAS patients's prognosis and may be attributed to patients's poor prognosis and can be attributed to their patient's rapid growth. miR-222-3p can negatively influence the luciferase activity of GAS5 in human vascular smooth muscle cells.

Source link: https://doi.org/10.1532/hsf.4739


Percutaneous transluminal angioplasty and stenting for recurrent carotid artery stenosis

Following endarterectomy, percutaneous transluminal angioplasty and stenting has been recently introduced as an alternative to surgical reexploration in patients with persistent carotid artery stenosis. The authors retrospectively reviewed their experience after 25 procedures in 21 patients to determine the safety and effectiveness of PTA, whether or not stenting for carotid artery restenosis. In several of these first cases, the authors decided to use PTA and stenting in the treatment of 18 arteries over the past three years due to early suboptimal results and recurrent stenosis. No neurological abnormalities ipsilateral to the treated artery had occurred in the 16 patients who each underwent at least six months of follow-up study, no developmental disorders ipsilateral to the treated artery had occurred after a mean follow-up period of 27 months. In two patients, three of five patients who underwent PTA alone developed severe asymptomatic restenoses that necessitated repeat angioplasty in one and PTA with stenting in two patients.

Source link: https://doi.org/10.3171/foc.1998.5.6.8


Angioplasty and stenting for carotid artery stenosis: indications, techniques, results, and complications

Following the promising results obtained in the treatment of coronary artery disease, combined angioplasty and stenting has been recommended for the treatment of carotid artery stenosis as well. Although the incidence of death and major stroke following angioplasty and stenting procedures matches favorably with surgery, new studies have shown that the incidence of perioperative transient neurological disorders and minor strokes may be higher than previously reported, especially in patients with new physical signs and u201d plaques.

Source link: https://doi.org/10.3171/foc.1998.5.6.6


Clinical considerations in the management of asymptomatic carotid artery stenosis

paraphrased artery stenosis, asymptomatic internal carotid artery stenosis in an aging population. Patients will have to be referred to antibiotic therapy options based on their individual risk profile and industry's knowledge of evidence-based studies obtained from large randomized control trials, according to professionals' experience. Before any randomized controlled trials, there has long been a lack of treatment guidelines for patients with asymptomatic carotid artery stenosis. In both symptomatic and asymptomatic patients, this has been investigated in a new random controlled trial, the Carotid Revascularization Endarterectomy Trial versus Stenting Trial, which compared carotid endarterectomy with angioplasty and stenting.

Source link: https://doi.org/10.3171/2011.9.focus11222


Predictive Value of Neutrophil-to-Lymphocyte, Aspartate-to-Alanine Aminotransferase, Lymphocyte-to-Monocyte and Platelet-to-Lymphocyte Ratios in Severity and Side of Carotid Artery Stenosis: Are Those Significant?

One of these arterial structures and occlusion of carotid artery can cause stroke or cranial infarction. platelet-to-lymphocyte, neutrophil-to-monocyte, lymphocyte-to-monocyte, and aspartate-to-alanine aminotransferase ratios were examined in this report. Methods: The research included one-hundred-fifteen patients with carotid artery stenosis between 50%-99% and 115 healthy controls with no carotid artery stenosis or additional disease. In the patient group, the relationship between the patient's side and severity of the lesion, lymphocyte-to-monocyte, neutrophil-to-monocyte, lymphocyte-to-monocyte, and aspartate-to-alanine aminotransferase ratios were investigated. In the terms of the same conditions, patients with carotid artery stenosis and healthy controls were compared to the healthy subjects. Conclusions: There were no statistically significant differences between the groups in terms of platelet-to-lymphocyte, neutrophil-to-lymphocyte, lymphocyte-to-monocyte, aspartate-to-alanine aminotransferase ratios, and degree of stenosis.

Source link: https://doi.org/10.1532/hsf.3431


Carotid artery stenosis with a high-intensity signal plaque on time-of-flight magnetic resonance angiography and association with evidence of intraplaque hypoxia

However, the role of intraplaque hypoxia prior to carotid endarterectomy and carotid artery stenting is not clear. METHODS: The investigation included nineteen consecutive patients with 20 carotid artery stenoses who underwent CEA at Saga University Hospital between August 2008 and December 2014, according to the participants. paraphrased plaques was also examined for the carotid plaques. RESULTS High-Intensity plaques on TOF MRA displayed higher expression levels of HIF-1u03b1 and VEGF compared to isointensity plaques, which were on isointensity plaques. The incidence of intraplaque hemorrhage on TOF MRA was also higher in the high-intensity plaques than in the isointensity plaques. Finally, the mean number of neovessels was significantly higher in those without plaque hemorrhage than in those with plaque hemorrhage. CONCLUSIONS Plaques with high-intensity signals on TOF MRA were accompanied by IPH and signs of intraplaque hypoxia.

Source link: https://doi.org/10.3171/2016.4.jns16349


Possible involvement of pericytes in intraplaque hemorrhage of carotid artery stenosis

OBJECTIVE The most common reason for intraplaque hemorrhage is neovessel ruptures; however, the reasons for intraplaque neovessel vulnerability remain uncertain. METHODS The authors retrospectively reviewed the medical records of all patients with carotid artery stenoses who had undergone carotid endarterectomy at their hospitals between August 2008 and March 2016. Patients with carotid plaques that could be evaluated histopathologically were eligible for study participation. Intraplaque hemorrhage was investigated using glycophorin A staining, and patients were divided into the following two groups based on the severity of granular staining: high IPH and low IPH. RESULTS Seventy of 126 consecutive carotid stenoses were rejected due to a lack of a specimen for histopathological examination; therefore, 53 patients with 56 carotid artery stenoses were eligible for study enrollment. Nonetheless, the densities of NG2- and CD146-positive neovessels in the high IPH group were much lower in the high IPH group than in the low IPH group.

Source link: https://doi.org/10.3171/2018.1.jns171942

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions