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The aim of this research was to investigate the sex difference and effects of blood pressure on the relationship between serum uric acid and carotid plaque in patients with coronary heart disease. Patients with CHD with SUA levels and carotid plaque was used to determine the effect of sex and BP on the relationship between SUA levels and carotid plaque. SUA results were significantly linked to the occurrence of carotid plaque under different BP states in the model of male BP subgroups, using the BP of group A as a model.
Source link: https://europepmc.org/article/MED/36617727
Abstract Clinical Practice Guidelines are based on systematic reviews of the available evidence and are useful tools to support clinical decision-making. The AGREE II instrument was used to perform a systematic review of the methodological integrity of carotid atherosclerotic disease clinical trials, published from 2000 to 2019. The appraisers independently assessed the CPG included in the analysis for each of the AGREE II's six domains. Five of the CPGs were awarded a high overall methodological quality rating, five were rated as moderate overall methodological quality, and two were rated as low overall methodological quality, and two were classified as poor overall methodological stability. The authors conclude that: The AGREE II device's review of carotid atherosclerosis clinical guidelines using the AGREE II system is feasible, with a high degree of agreement among appraisers; and that the majority of CPGs responsible for the care of atherosclerotic disease clinical guidelines are of high methodological quality.
Source link: https://europepmc.org/article/MED/PMC9716357
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