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In an anatomical image-based geometry with flow conditions closely matching physiological flows, researchers can learn how gas embolism affects carotid artery hemodynamics, numerical simulation of coupled Newtonian two-phase laminar flow with interface tracking are carried out. To understand how gas embolism affects carotid artery hemodynamics, numerical simulation of coupled Newtonian two-phase laminar flow and interface monitoring are performed. Significant deviation from flow without gas embolism has been recorded leading to non-standard flow distributions. Gas embolism leads to increased spatio-temporal fluctuations in the carotid artery hemodynamics, leading to higher time averaged shear stress values and higher areas of high oscillatory shear index, leading to elevated risk of atherosclerosis risk.
Source link: https://europepmc.org/article/MED/35643820
artery-to-artery embolism: We recently reported a troubling 30% chance of early neurological deterioration in a minor stroke with isolated internal carotid artery occlusion, mainly due to artery-to-artery embolism. Methods From a large multicenter retrospective database, we compared minor stroke isolated internal carotid artery occlusion patients treated within 4. 5 hours of symptoms onset with either IVT or antithrombotic therapy between 2006 and 2020. According to 46 and 60 patients, respectively, the END within 24 hours and END 7d occurred in 46 and 60 patients. However, both groups' scores did not significantly differ between the two groups, with the END 7d and 3-month modified Rankin Scale scoring ranging from 0 to 1 ranging from 0 to 1. Conclusion In our population of minor strokes in iICAO, the END rate was comparable between the two groups, but the END rate was similar between the two groups, with artery-to-artery embolism occurring earlier after IVT.
Source link: https://europepmc.org/article/MED/36073368
Intracranial carotid artery calcifications are a common finding on non-contrast computed tomography and have been attributed to an elevated risk of ischemic stroke. Although ICAC's Intimal, medial, and mixed subtypes of ICAC have been recognized, no studies are available on the connection between ICAC patterns and stroke etiology. The aim of our study was to find a correlation between ICAC numbers and etiological subtypes of ischemic stroke. We retrospectively reviewed a single center cohort of patients admitted for ischemic stroke with definite etiology. Patients with a first ischemic stroke with lacunar, cardioembolic, or atherothrombotic large artery disease etiology were included in the analysis. The association of ICAC patterns and stroke etiology was investigated using two logistic regression models adjusted for confounders. In conclusion, our analysis shows that intimal ICAC pattern is related to lacunar stroke, and if validated in further studies, it may be a predictor of lacunar stroke etiology.
Source link: https://europepmc.org/article/PPR/PPR541715
Background Two-layer stents have shown promising results in preventing periinterventional and postinterventional embolic events in elective settings of carotid artery stenting. paraphrased artery stenosis or occlusion with or without intracranial occlusion, we detail a single-center experience with the Cguard stent in the treatment of acute ischemic stroke due to symptomatic internal carotid artery stenosis or occlusion. Methods We retrospectively reviewed all patients who were given a CGUard stent in the setting of AIS at our hospital. In all patients, Stent deployment was successful. In three patients without early stent occlusion, transient acute in-stent thrombus formation occurred. After 49 days, a patient with acute stent occlusion was seen in 1 patient. In 2 patients, 1 patient sustained a transient ischemic attack 79 days after the procedure, and 1 patient developed sICH. In 12 patients, a favorable clinical outcome at 3 months was achieved in 12 patients, with a mortality rate of 24 percent.
Source link: https://europepmc.org/article/MED/36070140
The Surpass Streamline is Japan's most recently registered flow diverter as of January 2021. At Juntendo University Hospital, a total of 28 Japanese patients, including 9 clinical trial patients, underwent SS embolization, including 28 large or large internal carotid artery aneurysms. Due to the inability of finding the device in the tortuous parent artery, two patients died. Hence, 26 patients with 26 aneurysms were available for medical and anatomical examinations. Patients' mean age was 62. 6 years old, and 24 percent of them were female. In eight patients, the Aneurysmal mass effect increased in one and stayed stable. One patient with minor ischemic stroke fully recovered before 30 days, and our database showed a 7. 7% chance of major ipsilateral stroke and neurological death within 30 days. With a low risk of device-related complications, the SS embolization of large and unruptured ICA aneurysms provides positive anatomical and clinical results.
Source link: https://europepmc.org/article/MED/36070961
Introduction In space, a cephalad shift of body fluid equalizes the blood pressure throughout the body, resulting in various cardiovascular disorders. This research was done in the Department of Physiology, AIIMS, New Delhi, to determine the structure-function relationship of the carotid artery before and after HU of 14 days. Material and methods This study was performed in The Department of Physiology, AIIMS, New Delhi. 18 male Wistar rats weighing 250-300 gm were randomly divided into control and hindlimb unloaded groups and held in separate cages for 14 days, and hindlimb unloaded groups were randomly divided into control and hindlimb unloaded groups and housed in separate cages for 14 days. After H&E staining, a linear regression of mean arterial pressure and RR interval was used to derive the Baroreflex response. Conclusion The reduction in BRS after using pelvic suspension was reduced, but 15 days are not insufficient to produce any structural changes in the carotid artery.
Source link: https://europepmc.org/article/PPR/PPR539951
Purpose: Investigation into potential correlations between arterial transit artifacts and clinical signs, digital subtraction angiography, and dynamic susceptibility contrast perfusion imaging abnormalities in patients with carotid artery stenosis were investigated. Methods Forty-seven patients who underwent arterial spin labeling and DSC perfusion imaging in the same period were diagnosed with > 50% unilateral carotid artery stenosis by DSA in 24 hours after perfusion imaging was included. ASL in the distal middle cerebral artery trace was found in 68. 1%, 40% in the intracranial ICA and MCA traces, and 89 percent in the intracranial ICA trace. Conclusion The occurrence and localization of ATA in patients with CAS may provide vital insights into cerebral hemodynamics and CAS severity. Only in the distal MCA trace could indicate early-stage perfusion abnormalities and a moderate degree of stenosis, according to ATAs.
Source link: https://europepmc.org/article/MED/36067966
Purpose The aim of this article was to investigate the administration of tandem extracranial internal carotid artery and intracranial large vessel occlusion during endovascular thrombombectomy for acute ischemic stroke. Compared to those who were not treated with CAS during EVT, we wanted to investigate the results of AIS patients with tandem occlusion treated with carotid artery stenting. Acute Stroke, Methods We conducted a cohort study using data from AIS patients enrolled in the Italian Registry of Endovascular Treatment. Among the 466 AIS patients with TO, CAS patients, were 122, with no CAS patients being 226. After adjusting for variables associated with 3 months' mortality and successful recanalization, respectively, lower 3 months' mortality and higher rates of successful recanalization were reported with reduced 3 months' mortality and higher rates of successful recanalization. Conclusions Among AIS patients with TO, CAS, and EVT were correlated with a higher rate of successful reperfusion and a lower rate of 3 months' mortality.
Source link: https://europepmc.org/article/MED/36056270
Background The European Society for Vascular Surgery's recommendation is that vertebral revascularization and Ipsilateral CEA should not be performed in the same procedure. In 48 consecutive patients during a 5-year period, we discuss our experience with homochronous revascularization of V1 Segment of vertebral artery with Ipsilateral CEA and simple revascularization of the vertebral artery. Patients in group A and group B were not significantly different in terms of red blood cell removal, postoperative drainage volume, postoperative hospitalization days, and incidences of postoperative complications. Conclusion: Revascularization of vertebral artery and Ipsilateral CEA should be divided into revascularization of the V1 Segment of vertebral artery and revascularization of the vertebral artery with Ipsilateral CEA and revascularization of the vertebral artery with Ipsilateral CEA.
Source link: https://europepmc.org/article/MED/36058458
Background Ancestry Background There is a need for a unique atherosclerotic risk assessment for people living with HIV. Setting A machine learning classification system was used to analyze associative predictors of diagnosed carotid artery plaque plaques from low-to-intermediate cardiovascular risks in PLWH and control subjects with low-to-intermediate cardiovascular risks in order to find associative predictors of diagnosed carotid artery plaque plaques. Plaques were created with strain elastography in normal sections of the common carotid artery and traditional cardiovascular risk factors. Methods One hundred two PLWH and 84 control subjects were recruited from the prospective Canadian HIV and Aging Cohort Study. Plaque's presence was based on medical ultrasound scans of left and right common carotid arteries and internal carotid arteries. Random forest and logistic regression models were used to determine subjects with plaques. Conclusions Strain elastography contributes to the identification of individuals with carotid artery plaques as a risk factor.
Source link: https://europepmc.org/article/MED/35510848
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