Advanced searches left 3/3

Cardiovascular Endurance - Crossref

Summarized by Plex Scholar
Last Updated: 10 January 2023

* If you want to update the article please login/register

The impact of moderate endurance exercise on cardiac telomeres and cardiovascular remodeling in obese rats

Here we investigated the effects of a hypercaloric high-fat diet and regular exercise training on cardiac cell telomeres and histomorphometric indices of cardiac aging. Methods Ninety-six 4-month-old male Sprague-Dawley rats were fed for ten months of standard or a HFD diet. The expression of telomerase-reverse transcriptase as a marker of telomere-related senescence and apoptosis was investigated at the end of the study. In sedentary HFD and ND animals, the expression of Terf-1 and Terf-2 were similar. Notably, the combination of exercise and HFD increased senescence when compared to sedentary ND or HFD, as well as reduced RTL when compared to endurance ND animals. In comparison to all other groups, Exercising HFD animals also showed a trend toward higher Tert expression.

Source link: https://doi.org/10.3389/fcvm.2022.1080077

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions