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Thyroid hormones can influence homocysteine metabolism by regulating the methylenetetrahydrofolate reductase reductase. Using formulas, Castelli risk indices I&II, Atherogenic coefficient AEC, and Atherogenic Index of Plasma AIP were calculated. Hypothalon indices p 0. 001 and homocysteine p=0. 014 were markedly elevated in hypothyroid women when compared to euthyroid. Hypothyroid women and 25 percent of euthyroid women had hs-CRP > 3 mg/L, while 25 percent of euthyroid women and 25 percent of euthyroid women had hs-CRP > 3 mg/L. Conclusion: Premenopausal women with hypothyroidism have a higher risk of cardiovascular disease than those without.
Source link: https://doi.org/10.5937/jomb0-37007
Dyslipidemia is a significant modifiable risk factor for cardiovascular and metabolic diseases, which are responsible for a substantial number of deaths and disability around the world. Functional foods have been used around the world for thousands of years, particularly the prehispanic civilizations, who used several as medicinal foods. Although such foods are popular as dietary supplements for dyslipidemia and potentially reduce the associated cardiovascular risk, we find that for the majority of the listed functional foods, there are currently no data to back up its recommendation and every-day use.
Source link: https://doi.org/10.1024/0300-9831/a000290
Background: The body mass index is often used to determine the association of hypertension or dyslipidemia and obesity. This study is designed to determine whether BMI or WC is a more accurate predictor of hypertension or dyslipidemia in overweight/obese children and adolescents. Methods: The APV database held records on 81,819 patients from 189 nationwide pediatric obesity clinics in Germany, Austria, and Switzerland as of November 2012. Mean BMI-SDS was 2. 0 0. 5, and that mean WC-SDS was 2. 2 u00b1 0. 5. Both BMI-SDS and WC-SDS are more accurate predictors of hypertension and dyslipidemia than WC-SDS, although WC-SDS was marginally better at predicting adverse lipid profiles in predicting adverse lipid profiles. Obese patients with elevated systolic and diastolic blood pressure increased compared to normal-weight patients. If WC > 97th percentile was used, the difference was only +4. 8 mm Hg and +2. 6 mm Hg.
Source link: https://doi.org/10.1159/000354224
Despite statistics, many patients with cardiovascular disease are not achieving treatment targets. To determine whether lipid control needs to be modified, an international observational study was conducted to determine the prevalence of residual lipid abnormalities in statin-treated patients with CVD. Methods: In 11,104 patients with atherosclerotic CVD and a total of statin therapy, there were fasting plasma levels of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides. Patients with cerebrovascular disease only were least often found to have low HDL-C and elevated triglycerides. About two-thirds of statin-treated patients with CVD are not meeting lipid targets or have abnormal lipid levels, while patients with PAD can especially benefit from improved lipid control, while patients with PAD may be particularly benefited from improved lipid balancing.
Source link: https://doi.org/10.1159/000348859
Introduction: The present research sought to establish the role of lipid abnormalities and inflammatory markers for cardiovascular disease, as well as addressing obesity as a common comorbidity in patients with obstructive sleep apnea. Methods: The study was conducted as a prospective cohort study involving 120 patients with newly diagnosed OSA between 2019 and 2020 at the University Clinical Hospital Center in Belgrade, Serbia. A strong positive correlation was found between OSA severity and BMI, which were both associated with lipid, inflammation, and respiratory diseases, as well as the cardiovascular profile of patients with OSA. Conclusion: The findings of this research point to the pivotal role of dyslipidemia and inflammation, as well as coexistence of obesity in the pathogenesis of several conditions associated with an elevated risk of cardiovascular morbidity and mortality in patients with OSA.
Source link: https://doi.org/10.3389/fphar.2022.898072
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