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Cardiovascular Disease in China - Europe PMC

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Last Updated: 10 August 2022

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Modifiable risk factors associated with cardiovascular disease and mortality in China: a PURE substudy.

Methods and findings In this prospective cohort of 5262 middle-aged participants from 115 urban and rural communities in China's 12 provinces, it was examined how CVD incidence and mortality rates varied by sex, by urban-rural area, and by region. Four key risk factors, four demographic risk factors, education, poverty, grip strength, and household air pollution were evaluated in participants without prior CVD, population-attributable fractions for CVD, and mortality related to 12 common modifiable risk factors. Death rates in China's central and western areas were higher than those in the eastern region compared to the eastern region. The modifiable risk factors tested collectively contributed to 59% of the PAF for CVD and 56% of the PAF for death in China. Both CVD and mortality in men and women are higher in men than women, as well as in rural areas relative to urban areas.

Source link: https://europepmc.org/article/MED/35731140


The Associations between Exposure to PM2.5 Air Pollution and Incidence of Cardiovascular Disease in Yantai, China

After accounting for the effects of temperature and relative humidity, determining long-term trends and the day of week effects, a combination of Poisson-distribution generalized linear model and a generalized linear model were used to investigate the correlation between a daily variation of PM 2. 5 and cardiovascular disease prevalence, as well as the 95% confidence interval of the cardiovascular disease incidence lags. Every 10 u00b5g/m 3 increase in cardiovascular disease prevalence was correlated with a 0. 7 percent rise in cardiovascular disease incidence, and the most effect on cardiovascular disease incidence was found at a lag of 2 days for PM 2. 5. This study reveals that short-term exposure to PM 2. 5 may raise the risk of cardiovascular disease incidence and highlight the need for a stricter air quality level in Yantai, China.

Source link: https://europepmc.org/article/PPR/PPR519828


Cost-Effectiveness Analysis of Dapagliflozin Plus Standard Treatment for Patients With Type 2 Diabetes and High Risk of Cardiovascular Disease in China.

Using a Chinese healthcare system perspective, the aim of this report was to determine the long-term cost-effectiveness of dapagliflozin, in comparison to conventional therapy, for the treatment of adult patients with type 2 diabetes in adult patients with high cardiovascular risk. Methods A decision-analytic Markov model with one-year cycles was developed to determine the quality and economic outcomes in patients with T2DM and elevated risk of cardiovascular disease treated with standard care and dapaglifliflozin plus standard therapy for 30 years. Per QALY gained, up by 204% compared to three times the GDP per capita in 2021, but it was still expensive in China. These findings may help clinicians make the right treatment decisions for patients with T2DM at high risk of cardiovascular disease.

Source link: https://europepmc.org/article/MED/35910934

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions