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Aims We investigated the connection between cardiovascular autonomic neuropathy and chronic diabetic kidney disease in the event diabetic kidney disease. The first cardiovascular autonomic reflex tests were performed at baseline, and CAN was defined as 2 abnormal test findings. In a multivariable Cox regression model, patients with CAN's relative to those without CAN had a significant risk of incident DKD in comparison to those without CAN. Conclusion CAN is a useful indicator for long-term conditions, such as DKD in diabetics with type 2 diabetes, may be a good indicator of long-term problems.
Source link: https://europepmc.org/article/MED/34952039
Through a systematic review and meta-analysis, we wanted to find the prognostic association between cardiac autonomic neuropathy and cardiovascular disease events and mortality in type 1 and type 2 diabetes. Patients with and without CANs exhibited a pooled relative risk of 3. 16 percent of future CVE in favour of CAN. Sixteen studies from patients with and without CAN showed a unified relative risk of 3. 16 percent in favour of CAN. Patients with and without CAN were included in the all-cause mortality study, with a corresponding RR of 3. 17 in favour of CAN. In type 1 diabetes and with a definite CAN diagnosis, the risk of both future CVE and mortality was higher in type 1 than with type 2 diabetes and with a definite CAN diagnosis. This research shows the strong correlation between CAN and CVE and all-cause mortality. Implementation of population-based CAN screening will reveal a subgroup with disproportionately high cardiovascular and mortality risks that would allow for prompt intervention.
Source link: https://europepmc.org/article/MED/34969689
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