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Cardiovascular autonomic neuropathy is a typical difficulty of type 1 diabetic issues and is related to increased cardiovascular danger. Otherwise, some studies have discovered a high frequence of obstructive sleep apnea syndrome in T1D. The patients consisted of in this research will be patients with type 1 diabetic issues diagnosed for even more than 5 years. After over night polysomnography, cardiovascular autonomic neuropathy will be evaluated by different methods: study of HRV, cardiovascular autonomic reflex examination, measurements of urinary system degrees of catecholamines and measurements of sweat gland disorder utilizing Sudoscan. The seriousness of CAN will be reviewed in T1D patients with moderate to extreme OSAS contrasted to T1D patients with IAH < 15/ hr. A supplementary research is intended to evaluate the advancement of pens of the autonomic nerves after three months of treatment with CPAP in 15 patients with serious OSAS having formerly took part in the major research study.
Source link: https://clinicaltrials.gov/ct2/show/NCT03605329
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