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Cardiovascular - U.S. Department of Veterans Affairs

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Last Updated: 22 January 2023

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Two decade trends in cardiovascular disease outcomes and cardiovascular risk factors among US veterans living with HIV.

Coomprhensive studies on cardiovascular disease risk factors and HIV incidence in people living with HIV are limited. We calculated the prevalence and incidence of CVD risk factors and outcomes in the VA from 2001 to 2019, as well as the average annual percent changes in the estimates using retrospective data from 52,000 U. S. Veterans living with HIV who received care in the VA from 2001 to 2019. During the study period, the average age of the veterans increased from 47. 8 years to 58. 0 years. The AAPC's prevalence was highly relevant for the CVD findings and risk factors. The estimated prevalence of CVD risk factors and outcomes showed similar trends when adjusted for age. In conclusion, the prevalence and incidence of several CVD risk factors and outcomes in VLWH have risen over the past 20 years, according to a retrospective review of large-scale VA studies.

Source link: https://doi.org/10.1016/j.ijcrp.2022.200151


Characteristics and outcomes of severe COVID-19 in hospitalized patients with cardiovascular diseases in the Amazonian region of Brazil: a retrospective cohort.

In COVID-19, the northern region of Brazil is already vulnerable to other infectious diseases, and it was no different in COVID-19. In this area of the Amazon, the aim of this research is to determine the clinical correlates and outcomes of severe COVID-19 in hospitalized patients with and without CVD. Of these, 6011 did not have cardiovascular disease, and 3212 had some cardiovascular disease. invasive ventilation for patients with CVD was the first predictor of mortality, followed by chronic kidney disease, dyspnea, respiratory distress, cough, and cough. Only cough, not the high odds ratio in the predictors of CVD, varied among the non-carriers, and the high odds ratio in the predictors of death, but not vice versa. We also note the shorter life in CVD carriers, as well as the higher cardiovascular morbidity rate than other research.

Source link: https://doi.org/10.1038/s41598-022-23365-9


Radiotracers to Address Unmet Clinical Needs in Cardiovascular Imaging, Part 2: Inflammation, Fibrosis, Thrombosis, Calcification, and Amyloidosis Imaging.

The development of new radiotracers for PET and SPECT imaging is crucial in addressing the numerous unmet diagnostic requirements related to these changes. We discuss selected radiotracers that may help address key unmet clinical diagnostic needs in cardiovascular medicine in this two-part series. Part 1 addressed key scientific aspects relating to cardiovascular radiotracer manufacturing and reviewed emerging radiotracers for perfusion and neuronal imaging. Part 2 covers radiotracers for monitoring cardiovascular disease, thrombosis, fibrosis, calculation, and amyloidosis. We also cover emerging radiotracers for cardiovascular fibrosis imaging, such as those targeting fibroblast activation protein fibroblast activation protein.

Source link: https://doi.org/10.2967/jnumed.121.263507

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions