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Cardiovascular - OSTI GOV

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Last Updated: 22 January 2023

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Omega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution

Omega-3 polyunsaturated fatty acids, according to evidence, can attenuate the adverse cardiovascular consequences of exposure to fine particulate matter. However, it is also unknown if regular dietary intake of omega-3 PUFA shields against the cardiovascular risks of short-term exposure to low-level ambient air pollution in healthy participants. Sixty-two adults with low or elevated dietary omega-3 PUFA intake were included in the current study. Linear mixed-effects models were used to investigate the relationships between air pollutant concentrations and cardiovascular responses stratified by omega-3 intake levels. During the investigation period, the average concentrations of ambient PM 2. 5 and O 3 were well below the U. S. National Ambient Air Quality Standards. Conclusions This report shows links between short-term exposure to PM 2. 5 and O 3 in low blood pressures, as well as substandard cardiovascular responses, and substandard cardiovascular responses, and the fact that dietary omega-3 PUFA intake can help avoid such cardiovascular risks in healthy adults.

Source link: https://www.osti.gov/biblio/1905027


The influence of dietary intake of omega-3 polyunsaturated fatty acids on the association between short-term exposure to ambient nitrogen dioxide and respiratory and cardiovascular outcomes among healthy adults

This report seeks to determine if habitual omega-3 PUFA intake differs from those that promote respiratory and cardiovascular responses and short-term exposure to ambient NO 2. Methods Sixty-two healthy people were enrolled in low or high omega-3 PUFA groups based on their usual omega-3 PUFA intake. On the day of outcome assessment, four days before, and the 5-day moving average were obtained from an area air quality monitoring station. The associations between short-term exposure to NO 2 and the measured indices were tested using linear mixed-effects models stratified by omega-3 levels and adjusted by covariates including relative humidity and temperature. Conclusions The average concentration of ambient NO 2 during the study periods was 5. 3 u00b13. 8 ppb, which was below the National Ambient Air Quality Standards. An interquartile range increase in short-term NO2 concentrations in the high omega-3 group was significantly related to improved lung function [e. g. ]. At 5dMA, decreased blood lipids [e. g. , lowered blood lipids] decreased [e. g. , 1. 2% in FVC at lag1, 2. 6% in FEV1 at 5dMA]. An IQR rise in ambient NO 2 was attributed to coagulation markers and a decrease in HRV, but no correlation was found between short-term NO 2 exposure and changes in lung function, blood lipids, and vascular function in the low omega-3 group; however, null associations were established between short-term NO 2 exposure and changes in lung function, blood lipids, and vascular function. Conclusions and Conclusions The findings of this research indicate that dietary omega-3 PUFA intake may have respiratory and cardiovascular health benefits in response to short-term exposure of healthy adults to NO 2 levels below the NAAQS.

Source link: https://www.osti.gov/biblio/1905026

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions