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Cardiogenic - Springer Nature

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Last Updated: 10 September 2022

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Early hyperoxia and 28-day mortality in patients on venoarterial ECMO support for refractory cardiogenic shock: a bicenter retrospective propensity score-weighted analysis

Background The mortality risk for a patient with a refractory cardiogenic shock on venoarterial extracorporeal membrane oxygenation remains high, although hyperoxia may exacerbate this prognosis. In this context, the aim of the present research was to investigate the relationship between hyperoxia and 28-day mortality. Methods We conducted a retrospective bicenter survey in two French academic centers. Adult patients treated for refractory cardiogenic shock were included in the study population. Following admission, the absolute peak PaO_2, the mean daily peak PaO_2, the total mean PaO_2, and the degree of hyperoxia were recorded for 48 hours. The mean daily peak PaO_2, absolute peak PaO_2, and overall mean PaO_2 were independent predictors of 28-day mortality in a multivariate logistic regression analysis. Conclusions High oxygen levels were linked with 28-day mortality in patients on VA-ECMO care for refractory cardiogenic shock.

Source link: https://doi.org/10.1186/s13054-022-04133-7

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions