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Background In patients with coronary artery disease, ischaemic cardiomyopathy may result in progressive cardiac remodelling and left ventricular dysfunction. Perfusion imaging studies can be used to determine LV size and shape, mechanical retardation, and ejection fraction, as well as myocardial ischaemia and injury prevalences. We investigated the prevalence of LV remodelling in patients with CAD, as well as the relationship between LVR, LVMD, and EF. Patients with LVMD or low EF had higher EDV, SIES, and SIED, and SIED were all higher in patients with LVMD or low EF. Conclusions LVR is commonly seen in patients with CAD and can be detected long before symptoms of symptomatic heart failure are present. MPI is useful in estimating LVR by providing data about LV size and shape, which transitions from an ellipsoid to a spherical form in the development of ischaemic cardiomyopathy.
Source link: https://europepmc.org/article/MED/35848312
Background: The cardiovascular toxicity of radiotherapy may have an effect on cancer survival rates over the long term. Methods: We eventually recruited 40 patients for RT for thoracic tumors. We investigated the accuracy of 2D-STE in predicting CTRCD and heart systolic function decline, measuring the association between RT parameters and cardiac systolic function decline. The decreases in the LVGLS and LVGLS-Endo values between post- and post-treatment, as well as the LVGLS and LVGLS-Endo ratios were linearly linked to mean heart doses. The decreases in the LVGLS-Epi measurements between post- and pre-treatment, as well as the ratios of the decreases to baseline values were linearly correlated with the percentage of heart volume exposed to 5 Gy or more. Both the left and right sides of the heart were the same as patients with MHD over 2020 cGy in both the left and right directions.
Source link: https://europepmc.org/article/PPR/PPR507549
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