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Purpose: The aim is to investigate the effects of myocardial fibrosis on left ventricular diastolic filling patterns in triathletes compared to sedentary control by cardiac magnetic resonance imaging. Compared to controls, LGE-negative triathletes had similar EPFR but lower APFR, resulting in higher PFRR. Similar EPFR and decreased PFRR among LGE-positive triathletes, but with increased APFR and reduced PFRR. Compared to LGE-triathletes, the LGE + triathletes had an elevated LV mass index and extracellular volume fraction. Conclusions Athletic training results in a "supernormal" LV diastolic filling pattern in LGE-triathletic athletes, which may be attributable to increased LV myocardial flexibility and elasticity, which may be due to increased LV myocardial flexibility and elasticity.
Source link: https://europepmc.org/article/MED/36434969
Background Children with kidney disease have an elevated risk of cardiovascular morbidities in the early and post-transplantation period. Methods A prospective review was conducted to find longitudinal shifts in diastolic function and structure during pre- and post-kidney transplantation compared to healthy controls. E/e' lateral, E/A, interventricular septal end diastole diameter, left ventricular internal end diastole diameter, left ventricular posterior wall end diastole diameter, left ventricular posterior wall end diastole diameter, and left atrial dimension were all investigated by the left atrial dimension. Patients remained worse than controls until 30 months after transplant, and E/A was reduced at all time points relative to the controls. Left ventricular hypertrophy was associated with abnormal diastolic function and structure. Diastolic dysfunction and geometry partially recover after transplantation, but a subset of patients remains abnormal in comparison to healthy peers.
Source link: https://europepmc.org/article/MED/36357638
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