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Cardiac Arrest - Springer Nature

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Last Updated: 10 November 2022

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Acute Effects of Sodium Bicarbonate in Children with Congenital Heart Disease with Biventricular Circulation in Non-cardiac Arrest Situations

Despite the uproar surrounding the scandal, sodium bicarbonate is a commonly used medication in critically ill patients of all ages. After sodium bicarbonate therapy, there is a lack of data on the immediate effect on hemodynamic parameters, biomarker measures of cardiac function, and changes in vasoinotropic support. We analyzed arterial blood gases, heart rate, central venous pressures, cerebral and renal near-infrared spectroscopy changes in pediatric cardiac intensive care unit receiving bicarbonate therapy's changing in vasotropic and ventilator changes before and after sodium bicarbonate administration in a retrospective study on children with biventricular circulation in pediatric cardiac intensive care unit receiving bicarbonate therapy. The evaluation revealed Thirty-one administrations of sodium bicarbonate in 23 patients with congenital heart disease without residual shunts. After sodium bicarbonate administration in children with congenital heart disease with completely septated, biventricular circulation, no other significant changes were made after a change in serum pH and bicarbonate levels.

Source link: https://doi.org/10.1007/s00246-022-02905-0


The role of REBOA in patients in traumatic cardiac arrest subsequent to hemorrhagic shock: a scoping review

Purpose: The aorta is a useful adjunct to patients with severe hemorrhagic shock. Hypothetically, REBOA may help patients in severe cardiac arrest as balloon occlusion of the aorta increases afterload and may increase myocardial function leading to the return of spontaneous circulation. The effect of REBOA on patients in TCA was determined by a scoping study. This scoping review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Reviews' Statement. There were 785 patients in TCA who had received REBOA; these included 785 patients in TCA. This report shows that REBOA raises mean SBP in patients with TCA. ROSC's success after REBOA deployment ranged from 18. 2% to 67. 7%. Conclusions Overall, no data is available on the use of REBOA in patients in TCA.

Source link: https://doi.org/10.1007/s00068-022-02154-z


Machine learning to predict in-hospital cardiac arrest from patients presenting to the emergency department

In-hospital cardiac arrest in the emergency department is not unusual, but it is often fatal. We sought to predict ED-based IHCA in patients presenting to the ED based on triage results using the machine learning approach. By the region under the receiver operating characteristic curve, three supervised ML models were developed and tested, compared to the National Early Warning Score 2 and logistic regression model by the area under the receiver operating characteristic curve. Random Forest led the best AUC result out of the others, followed by Gradient Boosting and Extra Trees classifier. Although the differences between each of ML models and LR were not significant, all created ML models performed substantially better than using the NEWS2 scoring scheme. Our ML models demonstrated exceptional discriminatory ability in identifying EDCA based solely on triage results, based on the triage results.

Source link: https://doi.org/10.1007/s11739-022-03143-1


Comparison of the effects of lidocaine and amiodarone for out-of-hospital cardiac arrest patients with shockable rhythms: a retrospective observational study from a multicenter registry

This research was conducted in the hope of comparing the effects of lidocaine and amiodarone on patient with OHCA's prognosis and neurological outcomes in a real-world setting. After propensity score matching, we investigated the effects of lidocaine and amiodarone for patients with OHCA. The findings of the 51,199 patients who were registered in the OHCA registry were analyzed, including 1970 patients. The odds ratios and 95% confidence intervals of lidocaine use for 30-day survival and 30-day positive neurological results were 1. 44 and 1. 77, respectively, after doing PSM with amiodarone used as the standard. Conclusions The use of lidocaine and amiodarone for patients with OHCA in an international context showed no significant differences in short-term mortality or neurological outcomes in a real-world setting.

Source link: https://doi.org/10.1186/s12872-022-02920-2


Early prediction model of brain death in out-of-hospital cardiac arrest patients: a single-center retrospective and internal validation analysis

Background: A global organ shortage is a worldwide issue, and an increase in organ donation would be welcome by the global healthcare system. There is a donor organ shortage amid high demand for transplantable organs worldwide. Potential organ donors are potential organ donors, and early detection of patients with BD may aid in organ procurement. We therefore created a model for the early detection of BD in patients who survived the first phase of out-of-hospital cardiac arrests early. The multivariable logistic model's predictability scores of BD were based on u03b2-coefficients of prognostic variables established in the OHCA's multivariable logistic framework. Overall, 419 OHCA patients with ROSC were admitted to our hospital during the study period. After OHCA, we developed and internally validated a new prediction model for BD, which may have helped in the early identification of potential organ donors for early donor organ procurement.

Source link: https://doi.org/10.1186/s12873-022-00734-1


Cardiac arrest and complications during non-invasive ventilation: a systematic review and meta-analysis with meta-regression

Methods We conducted a systematic review and meta-analysis of studies published between 1981 and 2020 that included adults in whom NIV was used to treat acute respiratory failure statewide. We established the pooled incidence and confidence interval of NIV-related cardiac arrest per patient and then performed a meta-regression to determine the relationship with study characteristics. After meta-regression, NIV failure, and the study period, NIV's absence were all associated with NIV-related cardiac arrest, it was strongly associated with NIV-related cardiac arrest. Conclusion Cardiac arrest related to NIV occurred in one out of every 10,000 patients receiving ARF therapy under NIV. For NIV impairment, a NIV-related cardiac arrest was attributed to NIV failure.

Source link: https://doi.org/10.1007/s00134-022-06821-y


Public-access defibrillation and favorable neurological outcome after out-of-hospital cardiac arrest during the COVID-19 pandemic in Japan

OHCA's Early public-access defibrillation improves the outcomes of out-of-hospital cardiac arrests, but several initiatives to prevent the spread of coronavirus disease can delay the availability of PAD and exacerbate outcomes. This research seeks to investigate the effects of COVID-19 on PAD and OHCA outcomes in Japan, where PAD is well-documented. The proportion of patients with PAD and patients with one-month mortality with positive neurological results was determined by a cerebral performance category score of 1 or 2 within the study's statistical parameters. The number of OHCA patients who underwent PAD and had positive neurological outcomes progressively increased gradually from 2005 to 2019 increased steadily from 2005 to 2019. The percentage of patients with positive neurological outcomes was 25. 1% in 2019 and 21. 8 percent in 2020, respectively.

Source link: https://doi.org/10.1186/s13054-022-04220-9


Circular RNAs to predict clinical outcome after cardiac arrest

Background Cardiac arrest is the third leading cause of death worldwide. The promise of blood biomarkers may help clinicians with the ability to promote prognostication. This research seeks to identify circulating circular RNAs associated with clinical outcome after CA. In this research, whole blood samples were obtained 48 h after recovering spontaneous circulation in 588 people from California's Target Temperature Management trial. Two groups of 23 sex-matched patients found 28 circRNAs associated with neurological function and survival. CirculNFAT5 was upregulated in patients with poor outcomes in the TTM-trial, compared to patients with stable neurological results. When used in conjunction with established biomarkers of CA, we found circulating circRNAs associated with clinical outcome after CA, among which circNFAT5 may have the ability to aid in predicting neurological function and survival.

Source link: https://doi.org/10.1186/s40635-022-00470-7

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions