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Cardiac Arrest - ClinicalTrials.gov

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Last Updated: 10 September 2022

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Prediction of Intrahospital Cardiac Arrest Outcomes

Intrahospital cardiovascular arrest is one of the most common causes of death in hospitalized patients. Hospitalized patients in comparison to extramural cases of cardiovascular arrest, hospitalized patients typically have extensive medical disorders that can influence the outcome of resuscitation. Nevertheless, survival rates from resuscitation in hospitals are often higher in hospitals than in others, considering that there is often a rapid launch of resuscitation initiatives and predefined resuscitation criteria. The Design process at Kepler University Hospital's resuscitation registry includes retrospective data analysis of all data sets included in the resuscitation registry. Review of the registry for missing information as well as false alerts of the CPR team and, if necessary, removal of these data sets; analysis of the data sets using the machine learning technique random forest.

Source link: https://clinicaltrials.gov/ct2/show/NCT05466188


Thiamine as a Metabolic Resuscitator After Cardiac Arrest

This is a double-blind, placebo-controlled trial that will investigate the effects of intravenous thiamine on lactate, cellular oxygen intake, global oxygen consumption, and neurologic markers of neurologic injury following out-of-hospital cardiac arrest. Patients with spontaneous circulation following OHCA and have a lactate of 3 or more will be eligible for the study. Enrolled patients will be randomized to intravenous thiamine 500 mg twice a day for 5 doses or placebo equaling placebo.

Source link: https://clinicaltrials.gov/ct2/show/NCT03450707


Evaluation of the Optimal Time of Recognition of a Cardiac Arrest Within the EMS 95

Around 40,000 per year in France, the incidence of cardiac arrest in adults is about 40,000 per year. The majority of cardiac arrests occur in France, although the incidence of cardiac arrest in adults in adults is about 40,000 per year. According to studies, the time between the patient's death and the start of ECM is directly related to the survival rate after a cardiac arrest. According to other studies, a maximum delay of 90 seconds between the call to the ambulance and the recognition of the cardiac arrest should be the most beneficial for the patient, but is it achievable at the EMS 95? This research seeks to determine the standard time taken by Assistants of Medical Regulation to detect a cardiac arrest during the call to the EMS as well as the reasons that influenced this delay.

Source link: https://clinicaltrials.gov/ct2/show/NCT05523999


Pediatric Out-of-Hospital Cardiac Arrest Resuscitation: Evaluation of IM Epinephrine (The PRIME Trial)

The initial epinephrine dose, when administered with a child facing hospital cardiac arrest with no greater risk of injury, may be more effective. Including whether the use of IM epinephrine by autoinjector results in quicker administration of the initial doses of epinephrine without delaying time to definitive epinephrine; and the effect on spontaneous circulation have been determined and sustained.

Source link: https://clinicaltrials.gov/ct2/show/NCT05166343


Effect of Intermediate Airway Management Using an I-gelĀ® on Ventilation Parameters in Simulated Pediatric Out-of-Hospital Cardiac Arrest: Protocol for a Randomized Crossover Trial

Pediatric cardiac arrest is a high-risk, low-frequency disease epidemic that has caused death or severe neurological sequelae in survivors. The discussion about the most appropriate airway management tactic that should be used in pediatric OHCA is, however, still ongoing. To restore oxygenation in pediatric OHCA victims, first and emergency medical services generally use basic airway control techniques, i. e. , the use of a bag-valve-mask unit. In Second, the use of BVM is associated with gastric air insufflation. These results were worse after pediatric OHCA, according to a registry-based review, when emergency physicians used TI rather than supraglottic airway devices. The usage of SGA units [18], in accordance with the above-listed limitations of basic or advanced airway management systems, intermediate airway administration i. e. , could be a viable alternative in prehospital settings. Regurgitation and aspiration are not more common with IAM systems than with TI, and they are less likely than when a BVM device is used. There is increasing evidence that IAM systems can safely be used in children. In two pediatric studies of OHCA, American paramedics had significantly higher success rates with SGA units than with TI. However, data regarding the effects of IAM with an i-gelu00ae versus a BVM on respiratory parameters during pediatric OHCA is missing. The assumption behind this research is that early introduction of an i-gelu00ae device without prior BVM ventilation may raise ventilation quality in comparison to the conventional approach consisting of BVM ventilations.

Source link: https://clinicaltrials.gov/ct2/show/NCT05498402

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions