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Cardiac Amyloidosis Scintigraphy - Crossref

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Last Updated: 09 August 2022

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Census of Cardiac Uptake on Routine Bone Scintigraphy, a Methodology to Assess the Prevalence of the TTR Amyloidosis

Diagnosis decisions cannot be based on echography and MRI results alone because they lack certainty. Our research focuses on a single institution retrospective study aimed at determining the bone scintigraphies and the prevalence of transthyretin cardiac amyloidosis in our population. Methods: We've published a survey of the incidental cardiac uptake in routine bone scintigraphy in 2211 consecutive patients enrolled between 2009 and 2020, the bulk of which were performed for oncologic reasons. The cardiac uptake in grades 2 and 3 is classified into three levels of gradation, causing the diagnosis of the TTR cardiac amyloidosis in grades 2 and 3. In 1. 37 percent of all patients, different degrees of myocardial uptake were found. Conclusion: The careful review of all incoming adult patients' bone scintigraphy will enable us to diagnose the TTR cardiac amyloidosis at a preclinical level and develop new ethical therapies.

Source link: https://doi.org/10.31487/j.jicoa.2022.02.01


Abstract 233: A Network Meta-analysis Comparing The Performance Of Magnetic Resonance Imaging, Positron Emission Tomography And Bone Scintigraphy Techniques In Detecting Cardiac Amyloidosis

Aims: Diagnosing cardiac amyloidosis using non-invasive imaging methods can be daunting. Methods: The aim of this paper was to determine studies comparing the diagnostic results of CMR, PET, or BS in diagnosing cardiac amyloidosis, where histopathological examination of endocardial biopsy tissue or extra-cardiac organs was used as reference standards. We used an arm-based hierarchical framework to explore the inherent correlation between sensitivity and specificity, as well as varied tests used in each study. The various imaging techniques used to diagnose cardiac amyloidosis were calculated by sensitivity, specificity, and superiority. Overall, the study quality assessed by QUADAS-2 was generally solid, with no evidence of bias. Conclusion: Several non-invasive imaging techniques have been tested for diagnosing cardiac amyloidosis with varying sensitivity and specificity.

Source link: https://doi.org/10.1161/circoutcomes.15.suppl_1.233

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions