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Cardiac Action Potential - Astrophysics Data System

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Last Updated: 12 October 2021

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Effects of stochastic channel gating and distribution on the cardiac action potential

We explored the impacts of stochastic present changes and channel circulations on action potential period, intercellular transmission delays and transmission blocks using a changed ventricular cell design with Markovian formulations of the major ion currents and with network counts drawn from Poisson distributions. In solitary cells, APD variability was basically caused by stochastic network gating of I Ks, relentless I Na and I Ca, L. In cell strands, ICD irregularity induced by stochastic channel gating and Poissonian network circulations was low under typical conditions.

Source link: https://ui.adsabs.harvard.edu/abs/2011JThBi.281...84L/abstract


Artificial neural network model for predicting changes in ion channel conductance based on cardiac action potential shapes generated via simulation

Nonetheless, no studies have been conducted to forecast the sort of healthy protein network irregularities that take place with an action potential form. In the AP simulation, we enhance and decrease the conductance of each ion network at a constant rate, leading to 1,980 AP forms and one conventional AP form with no changes in the ion channel conductance. Consequently, we determine the AP distinction forms between them and use them as the input of the machine learning design to anticipate the changed ion network conductance.

Source link: https://ui.adsabs.harvard.edu/abs/2021NatSR..11.7831J/abstract


All-digital, real-time preprocessor for automated analysis of cardiac action potentials

Automated evaluation of cardiac action possibilities was applied in real-time by an all-digital system making use of three digital signal microprocessors. The preprocessor examples the analog signal at 1 μs fixed intervals and immediately determines both the signal smoothing and the local line segment signal approximation.

Source link: https://ui.adsabs.harvard.edu/abs/1996Meas...19....1I/abstract

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions