* If you want to update the article please login/register
Prostate cancer is the second most common cause of cancer-related death in males in males. Bone and regional lymph nodes are the most common sites of prostate cancer metastases, followed by lung, liver, and brain. We present herein a patient of prostate cancer with omental metastases and peritoneal carcinomatosis, ascites, but no bone metastases have been found. Prostate cancer can cause distant metastases in unexpected locations. No. 13, No. 13; No. 13, No. 13: No.
Source link: https://doi.org/10.3329/kyamcj.v13i2.61344
Until now, only 32 cases of prostate cancer with peritoneal carcinomatosis and ascites have been reported in the literature. We present the first reported case of prostate cancer with peritoneal carcinomatosis and malignant ascites whose treatment was complicated by tumor lysis syndrome as well as a literature review of similar cases. We present a rare example of a 78-year-old retired Caucasian male with recurrent metastatic prostate cancer and malignant ascites. Conclusions : Ascites formation in prostate cancer patients leads to poorer prognosis than non-ascitic variants. Ascitic fluid prostate specific antigen analysis can help with diagnosis of malignant ascites in cases of diagnostic uncertainty. Patients with tumor lysis syndrome treated for prostate cancer will be able to identify patients in whom prophylaxis may be helpful.
Source link: https://doi.org/10.12688/f1000research.121639.1
Abstract: Tumor agnostic circulating tumor DNA is routinely used to inform treatment decisions in gastrointestinal cancers, particularly metastatic cancers. The amount of ctDNA detected in plasma is influenced by age, tumor burden, and tumor vascularization. We hypothesized that peritoneal carcinomatosis is associated with reduced ctDNA levels than other metastatic sites in GI cancers due to the plasma-u2013peritoneal barrier. Methods We performed a retrospective review of patients with stage IIu2013IV GI cancers treated at our hospital between 2015 and 2020 with available panel-based ctDNA results – including available panel-based ctDNA results. We compared the estimated maximum variant allele frequency of somatic mutations across metastatic locations. Output: Results Of the 279 patients with GI cancers had stage IV disease, 212 had stage IV disease. PC was associated with lower ctDNA levels in patients with stage IV disease, regardless of the primary tumor site. Conclusions PC of GI origins is associated with significantly lower ctDNA levels when compared to visceral metastasis.
Source link: https://doi.org/10.1245/s10434-022-12399-y
Several experiments related to intact plant vascular structures, with u201d respiratory bodiesu201d surrounded by a foreign bodyu2013type multinucleated giant cell reaction in pulse granulomas. We discuss a case of a 70-year-old male patient presenting to our hospital for an incisional hernia repair. Several peritoneal whitish nodules and one subserosal appendicial nodule were discovered during the hernia repair procedure. Nodular lesions found in the subserosa were found to be pulse granulomas, according to microscopic examination. We present a case of pulse granuloma with spiral glands complicating percutaneous duodenal ulcer and mimicking peritoneal carcinomatosis in this paper.
Source link: https://doi.org/10.1177/1066896918761234
Introduction High-grade serous primary peritoneal cancer is remarkably sensitive to platinum-based chemotherapy, with response rates above 80%. Patients with moderate to severe reactions are expected to have either 15% and 20%, with most commonly seen after a median of 6u20138 infusions. Report on case An 62-year-old female patient with stage IIIC primary serous carcinoma of the peritoneum was diagnosed and chemotherapy with carboplatin and Paclitaxel was recommended by the oncology service and patient. Skin, pulmonary, cardiac, and atypical signs are present in the eight cycle of carboplatin, and atypical findings were identified within 40 mins of administration. The test result was positive, with a dose of 10 mg/ml on the skin. Prolonged carboplatin use has been attributed to an elevated risk of carboplatin-related hypersensitivity reactions.
Source link: https://doi.org/10.1177/10781552221074975
Patients can benefit from newer treatment options that are promptly identified in cases where peritoneal carcinomatosis is present, and they are referred to specialized centers. Three types of machine learning approaches were used: a neuro-evolutive network based on artificial neural network, support vector machines, and random forests, all mixed with differential evolution in order to determine the presence or absence of peritoneal carcinomatosis in colorectal cancer patients. The best results were found during the testing phase, according to the RF strategy.
Source link: https://doi.org/10.3390/healthcare10081425
This research was conducted in rats and was evaluated for toxicity using collagenase in peritoneal cavity as a preliminary step toward establishing a treatment that does not apply in human surgery or HIPEC. Only 8 pigs were treated with peritoneal lavage, according to the author. Pre-treatment, post-treatment, and 24 hours after therapy were collected, according to blood and peritoneal fluid samples. Both MMP1 and MMP2 were tested in all samples, and no differences were found in blood collagenase levels between pre-treatment, post-treatment, and 24 hours post-treatment.
Source link: https://doi.org/10.21203/rs.3.rs-970756/v1
Abstract Background: The only curative therapy for pseudomyxoma peritonei arising from the appendix is complete cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. A rise risk of surgical complications is attributed to a high peritoneal carcinomatosis index. Patients with elevated PCI will be able to report the findings of a proposed two-step surgical program to reduce postoperative morbidity and improve resectability of patients with elevated cyphoi. Methods All patients who underwent a planned two-step surgical approach for PMP between January 2012 and March 2020 were included in the study. Complete CRS of the inframesocolic compartment and omentectomy were both performed during the first surgery. Seven children had a low-grade fever and one had a high-grade disease. At the second surgery, one patient was classified as unresectable. Conclusions Two-step surgical treatment for low-grade PMP patients with elevated PCI is safe and effective, with acceptable postoperative morbidity and no compromise on oncologic outcomes.
Source link: https://doi.org/10.21203/rs.3.rs-88869/v1
To review the available clinical evidence pertaining to the use of Indocyanine Green fluorescence imaging for intraoperative detection of peritoneal carcinomatosis. According to the PRISMA guidelines, we performed a systematic review of a clinical series looking at the possibility of ICG fluorescence imaging in detecting peritoneal carcinomatosis during surgical treatment of abdominal malignancies. Patients and cancer samples, date, dose, and modality of ICG therapy, as well as the accuracy of fluorescence diagnosis of peritoneal nodules were collected and analyzed. In 28 cases, hepatocellular carcinoma in 16 cases, ovarian cancer in 16 cases, ovarian cancer in 26 cases, and endometrial cancer in one case, the investigated tumors were colorectal carcinomas, hepatocellular carcinoma in 16 cases, hepatocellular carcinoma in 16 cases, ovarian cancer in 16 cases, and endometrial cancer in one case. The studies showed that ICG management's technical results were consistent across the studies. peritoneal carcinomatosis patients with colorectal, hepatocellular, ovarian carcinomas have a promising intraoperative method for detection and characterization of peritoneal nodules in patients with peritoneal carcinomatosis.
Source link: https://doi.org/10.21203/rs.3.rs-26024/v2
To review the available clinical evidence relating to the use of Indocyanine Green fluorescence imaging for intraoperative detection of peritoneal carcinomatosis. According to the PRISMA guidelines, we carried out a systematic analysis of the possibility of ICG fluorescence imaging in detecting peritoneal carcinomatosis in abdominal malignancies surgical treatment. Trials with fluorophores other than ICG were refused for trials. Data on patients and cancer features, chronology, dose, and modality of ICG administration, increased visibility, specificity, and accuracy of fluorescence diagnosis of peritoneal nodules were gathered. In 28 cases, colorectal carcinoma, hepatocellular carcinoma in 16, ovarian cancer in 16 cases, ovarian cancer in 26 instances, and endometrial carcinoma in one case. The ICG management's scientific results remained consistent throughout the studies. peritoneal carcinomatosis patients with colorectal, hepatocellular, and ovarian carcinomas are a promising intraoperative method for finding and determining peritoneal nodules. peritoneal carcinomatosis is a common intraoperative device for detecting and evaluating peritoneal nodules in patients with colorectal, hepatocellular, ovarian carcinomas.
Source link: https://doi.org/10.21203/rs.3.rs-26024/v1
* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions