Carcinoma Esophagus - Europe PMC

A diagnostic pitfall; Small cell carcinoma-like features in basaloid squamous cell carcinoma of the esophagus.

Esophageal basaloid squamous cell carcinoma can mimic small cell carcinoma biopsy specimens and cause pathology diagnostic difficulties. We wanted to establish the clinicopathological significance of small cell carcinoma-like morphologies in basaloid squamous cell carcinoma. The esophageal basaloid squamous cell carcinoma specimens were reviewed and compared to 13 matched surgical specimens. CD56 was present in 42% of basaloid squamous cell carcinomas with small cell carcinoma-like features, and immunohistochemically, synaptophysin, and chromogranin A were all negative, though chromogranin A were consistently negative, while chromogranin A was largely absent, and synaptophysin and chromogranin A were also absent, while synaptophysin and chromogranin A In all cases of basaloid squamous cell carcinoma, a p40 was present. If CD56 is the only neuroendocrine marker used, small cell carcinoma-like features may lead to a misinterpretation of a true small cell carcinoma. In basaloid squamous cell carcinoma, p16 expression can also be detected.

Source link: https://europepmc.org/article/MED/35861388

Epithelial-Myoepithelial Carcinoma of the Esophagus: A Case Report.

Epithelial-myoepithelial carcinoma of the esophagus is a rare biphasic tumor with low malignant risk that has not been previously reported in the scientific literature. During a gastroscopic examination, the patient was diagnosed as asymptomatic, 53-year-old male who revealed EMC in the esophagus. The wall of the lower esophageal wall thickening of the lower esophageal wall thickness of about 0. 7 cm was revealed on a 0. 6 cm thickened esophageal wall, according to an enhanced scan, which revealed uneven change in the thickened esophageal wall.

Source link: https://europepmc.org/article/MED/35874132

Clinical features of superficial esophagus squamous cell carcinoma according to alcohol-degrading enzyme ADH1B and ALDH2 genotypes.

Inactivated alcohol dehydrogenase and aldehyde dehydrogenase are two distinct disorders that can be related to esophageal carcinogenesis. SCC, head and neck, and metachronous squamous cell carcinoma were also investigated. Methods We conducted a single-center, retrospective review of patients with ESCC treated by endoscopic resection. Among the 297 enrolling patients and patients in the double-inactivated program, 60% of them were under the age of 50 years old, with 60% of them being u2264 50 years old. More ESCCs were found in the upper esophagus and more multiple ESCCs were also present in this group, as well as more simultaneous multiple ESCCs. Multiple patients had multiple Lugol-voiding lesions and heavy alcohol users, with more than half of the patients suffering multiple Lugol-voiding lesions and heavy alcohol users. As risk factors for metachronous ESCC, multivariate analysis revealed connections in the upper esophagus, multiple LVLs, and history of HNSCC as risk factors for metachronous ESCC. Conclusions & Coordination Activation kinetic enzymes were found to the onset of ESCC, lesion site, and metachronous ESCC and HNSCC.

Source link: https://europepmc.org/article/MED/35788888

Verrucous carcinoma of the esophagus with complete response after chemoradiotherapy.

Surgical carcinoma of the esophagus is a rare abnormal tumor that is difficult to recognize. VCE treatment for VCE are the same as for standard esophageal cancer, requiring combined chemotherapy, surgical resection, and radiation therapy. After CRT is announced, it is a case of VCE with complete response after VCE is presented. Case report A four-year-old man was discovered with white, irregular esophageal mucos four years ago. Two-stage esophagectomy was performed four weeks after the conclusion of CRT. After primary suture of the hole, a latissimus dorsi flap was patched to the bronchus. The gastric tube was rebuilt through the antethoracic route six weeks after, six weeks later. The pathological findings revealed CR to CRT, but there were no proliferative cancer cells in the specimen. Since the resection, the patient has had no recurrence for three and half years. CRT may be a suitable treatment for VCE in cases where local resection is a challenge for local resection.

Source link: https://europepmc.org/article/MED/35781764

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