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Carbon Quantum Dots - Europe PMC

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Last Updated: 28 December 2022

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Gentamicin-loaded chitosan/folic acid-based carbon quantum dots nanocomposite hydrogel films as potential antimicrobial wound dressing.

Various carbohydrate polymers are commonly used in wound dressing films to promote wound healing in the wound. In the simulated wound media, the GM release profile displayed a controlled release speed over 48 hrs with a low initial burst release. According to the results, a significant rise toward multiple gram-positive and negative bacterial strains, as well as a desired cytotoxicity against Human skin fibroblast cells were found in vitro. The obtained findings show that CQDs-crosslinked CS nanocomposite as a potent antimicrobial wound dressing.

Source link: https://europepmc.org/article/MED/36544213


New Insights into the Cellular Toxicity of Carbon Quantum Dots to Escherichia coli.

In vitro, the cytotoxicity and toxic mechanisms of carbon quantum dots to E. coli were investigated in this research. Within a short culture time, CQDs demonstrated excellent biocompatibility with E. coli. CQDs modified cell wall charges and induced lipid peroxidation on the surface of E. coli, resulting in an increase in cell wall permeability. CQDs could cause DNA damage, which may prevent the propagation of E. coli.

Source link: https://europepmc.org/article/MED/36552683


Novel Green Fluorescent Probe Stem From Carbon Quantum Dots for Specific Recognition of Tyrosinase in Serum and Living Cells.

Hence, this paper developed a one-step hydrothermal method that used catechol, citric acid, and urea as precursors for tyrosinase activity detection by one-step hydrothermal method. With a low detection limit, the validated TYR-CQDs displayed excellent linear correlation and a broad linear range, with a low detection limit, which demonstrated high reliability and recovery in quantitative determination of TYR in human serum samples.

Source link: https://europepmc.org/article/MED/36515759


High fluorescence performance lignin-based carbon quantum dots prepared by supercritical catalytic and solvothermal treatment for target tumor labelling

Lignin was first cracked using an ethanol supercritical/noble metal catalyst, and then, the L-CQDs were made with the cracked lignin fragments as carbon precursors without using any modified reagents. The L-CQDs-1, which contains significant molecular weight compounds, is comparable to the OL-CQDs produced by the traditional one-pot hydrothermal method, are comparable to the OL-CQDs prepared by the conventional one-pot hydrothermal method, and have photoluminescence and excellent up-conversion photoluminescence, which have increased by 15 times and 60 times, respectively, respectively. The prepared FA@L-CQDs-1 display the ability to target and label tumor cells when L-CQDs-1 were mixed with, and quenched by folic acid.

Source link: https://europepmc.org/article/PPR/PPR584360


Rapid and Sensitive Detection of Rutin in Food Based on Nitrogen-Doped Carbon Quantum Dots as Fluorescent Probe.

As the fluorescent probe, the aim of this research was to develop a fast detection device of rutin in food based on nitrogen-doped carbon quantum dots. The absorption ability and fluorescence intensity of N-CDs were also determined using the respective spectroscopy methods. N-CDs fluorescent probes were also tested on this basis. The synthesized N-CDs were amorphous carbon structures with excellent water solubility and optical properties, with a high yield of 24. 1%. Rutin had a potenti-quenching effect on N-CDs, and the procedure demonstrated good linearity when the concentration of Rutin was in the range of 0. 1-400 bcg/mL in a phosphate-buffered solution at pH = 7. 0, with a detection limit of 0. 033 bcg/mL. The black buckwheat tea and wolfberry tree grew to 93. 98-104. 2 percent during the summer, with relative standard deviations in the range of 0. 35 to 4. 1 percent.

Source link: https://europepmc.org/article/MED/36557970


Carbon quantum dots with pH-responsive orange-/red-light emission for fluorescence imaging of intracellular pH.

As a precursor, solvothermal method for the determination of pH fluctuation in HeLa cells by fluorescence imaging was used in the preparation of pH meter dots with polyaminobenzene hydrazine as precursor. As demonstrated by successful monitoring of intracellular pH changes in HeLa cells, the sensor has high sensitivity and reversibility, as well as anti-interference capability, allowing sensing pH changes in the intracellular environment in real time.

Source link: https://europepmc.org/article/MED/36512123


Milk-Derived Carbon Quantum Dots: Study of Biological and Chemical Properties Provides Evidence of Toxicity.

Carbon dots are a carbon-based zero-dimensional nanomaterials that can be made from a variety of organic precursors. The absorption spectra show the absorption band at 280 b1 3 nm as shown by the absorption spectrum, which includes C=O and C-H bond, as well as nitrogen-based bond like C-N, C=N, and -NH2 presence in CDs. To determine the toxicity of CDs for murine hippocampal cells, the Presto Blue procedure was used. The cytotoxic effect was decreased in 1 and 2 h synthesized CDs, although the toxicity was higher for lower synthesis times of 1 and 2 h, as the concentration was reduced in 1 and 2 h synthesized CDs, resulting in a survival rate of 60-80%. According to the number of viable cells by 40%, CDs can have a concentration and time-dependent cytotoxic effect, as shown by the cytotoxicity report.

Source link: https://europepmc.org/article/MED/36557861


Electrochemical (bio)sensors based on carbon quantum dots, ionic liquid and gold nanoparticles for bisphenol A.

For the manufacturing of the BPA sensor, screen printed carbon electrode was modified with ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate, carbon quantum dots, and gold nanoparticles. The central composite design process was optimized for AuNP deposition time, amount of CQD, and percentage of IL using the electrode surface composition technique. The Ty/Au00d7 10 -8 M and the Au00d7 10 -9 M respectively, according to laboratory results, the linear dynamic range and detection limit of the BPA sensor were determined by differential pulse anodic adsorptive stripping voltammetry and the AuNP/CQD-IL/SPCE sensor revealed a linear response to BPA in the range of 2. 0 - 0. 8 - 9 M. The sensors' analytical applicability to the analysis of BPA in mineral water samples was also tested.

Source link: https://europepmc.org/article/MED/36473678


Functional Carbon Quantum Dots for Ocular Imaging and Therapeutic Applications.

Carbon quantum dots are a class of emerging carbonaceous nanomaterials with a unique fluorescent quality, extremely small size, ability to penetrate cells and tissues, ease of manufacturing, surface modification, low cytotoxicity, and excellent water dispersion are all three characteristics. Functionalized CDs, which have been produced in a convenient therapeutic agent for ocular disorders, are a promising therapeutic candidate for ocular diseases.

Source link: https://europepmc.org/article/MED/36461689


Phosphonic acid tagged carbon quantum dots encapsulated in SBA-15 as a novel catalyst for the preparation of N-heterocycles with pyrazolo, barbituric acid and indole moieties.

phosphonic acid tagged carbon quantum dots of CQDs-N 2 encapsulated and assembled in SBA-15 channels for this purpose, according to a post-modification program. Several techniques were used to describe the mesoporous catalyst of functionalized carbon quantum dots. Under the solvent-free atmosphere, at 100 °C under solvent-free conditions, an excellent catalyst was used for the manufacture of novel pyrazolo[4,3]pyrimidine derivatives by using pyrazole, barbituric acid, and indole moieties.

Source link: https://europepmc.org/article/MED/36460684

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions