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Carbon Monoxide Poisoning - DOAJ

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Last Updated: 28 September 2022

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Extracorporeal Hyperoxygenation Therapy (EHT) for Carbon Monoxide Poisoning: In-Vitro Proof of Principle

Carbon monoxide poisoning is the leading cause of poisoning-related deaths worldwide. Extracorporeal hyperoxygenation therapy for CO poisoning treatment eliminates the CO by treating blood extracorporeously at elevated oxygen partial pressure. We first established the connection between a hollow fibre membrane oxygenator and a specifically designed batch oxygenator based on the bubble oxygenator principle at elevated pressures in this research.

Source link: https://doi.org/10.3390/membranes12010056


High-Sensitivity Troponin I and Creatinine Kinase-Myocardial Band in Screening for Myocardial Injury in Patients with Carbon Monoxide Poisoning

Myocardial dysfunction due to acute carbon monoxide poisoning is common and is correlated with poor outcomes. This single-center, retrospective cohort study of 905 consecutive adult patients in the CO poisoning registry from February 2009 to December 2019. Initial and peak hsTnI and CK-MB levels were both elevated in patients with cardiomyopathy and initial BNP levels were significantly higher in patients with cardiomyopathy than in non-cardiatry patients, but AUCs were higher for hsTnI and CK-MB than for BNP. Patients at a high risk of CO-induced cardiomyopathy can be identified by elevated hsTnI or CK-MB on admission, which can also be a screening tool for CO poisoning.

Source link: https://doi.org/10.3390/diagnostics10040242


Cerebral White Matter Lesions on Diffusion-Weighted Images and Delayed Neurological Sequelae after Carbon Monoxide Poisoning: A Prospective Observational Study

Introduction: Carbon monoxide poisoning can result in delayed neurological sequelae. This study seeks to determine if acute brain lesions discovered using diffusion-weighted magnetic resonance imaging following acute CO poisoning are related to DNS generation. Methods: This prospective review was based on patients with CO poisoning treated at a university hospital in Bucheon, Korea, and was published in a journal. Results: In 49 patients and DNS cases, acute brain lesions on MRI were noted in 49 patients, and DNS occurred in 30 patients out of 154 patients. Conclusion: The presence of ABLM in white matter was largely related to the occurrence of DNS. Patients with CO poisoning may need early detection of the possibility of developing DNS by MRI may be beneficial in treating patients with CO poisoning.

Source link: https://doi.org/10.3390/diagnostics10090698


Association between Glasgow Coma Scale in Early Carbon Monoxide Poisoning and Development of Delayed Neurological Sequelae: A Meta-Analysis

Since acute carbon monoxide poisoning, a significant number of people suffer delayed neurologic sequelae. The Glasgow Coma Scale can be used to predict delayed neurologic sequelae occurrence with certainty and without any limitations. Through a meta-analysis, we investigated the relationship between a poor GCS score found in cases of early CO poisoning and delayed neurologic sequelae development. We searched MEDLINE, EMBASE, and the Cochrane Library for studies on GCS as a predictor of delayed neurologic sequelae in patients with CO poisoning in June 2021. Patients with acute CO poisoning posed a significant risk in delayed neurologic sequelae growth, according to those with a low GCS score, with a significantly higher value and moderate heterogeneity. Early CO poisoning patients' first low GCS score was attributed to the occurrence of delayed neurologic sequelae.

Source link: https://doi.org/10.3390/jpm12040635


Association between Early Phase Serum Lactate Levels and Occurrence of Delayed Neuropsychiatric Sequelae in Adult Patients with Acute Carbon Monoxide Poisoning: A Systematic Review and Meta-Analysis

The primary aim of treating carbon monoxide poisoning is to avoid or minimize the occurrence of delayed neuropsychiatric sequelae. Hence, testing patients with a high risk of DNS occurring at the earliest is crucial. This systematic review and meta-analysis looked at the relationship between early phase serum lactate levels and the occurrence of DNS in adult patients with acute CO poisoning. Adult patients with CO poisoning and reported initial lactate concentrations were obtained from Embase, MEDLINE, Google Scholar, and six domestic databases in January 2022. In adult adults with acute CO poisoning, the early phase serum lactate concentration was significantly higher in the DNS group than in the non-DNS group. The DNS group had a significantly higher lactate concentration than that in the non-DNS group.

Source link: https://doi.org/10.3390/jpm12040651


Prevalence of hidden carbon monoxide poisoning in auto service workers; a prospective cohort study

Carbon monoxide is produced as a result of incomplete combustion of hydrocarbon-containing fuels such as natural gas, coal, liquid petroleum gas, and wood. We wanted to test CO levels in auto care repairmen with persistent CO-related ailments using a serial, non-invasive approach in this research. After the third experiment, the highest mean COHb value was 7. 4% u00b1 3. 32%. Discussion We discovered that the threat of being affected by CO is greatest in buildings in which the vehicle services were located. The effects of chronic or prolonged exposure to small amounts of CO were found to be ambiguous. However, it was found that low-grade CO exposure could lead to coronary artery disease and some neurological disorders in certain studies. Conclusions We've come to the conclusion that more comprehensive research into chronic CO poisoning is required.

Source link: https://doi.org/10.1186/s12995-018-0214-9


Epidemiological Study of Deaths due to Carbon Monoxide Poisoning Referred to Forensic Medicine in Mazandaran, Iran

History: Carbon monoxide poisoning is the most common cause of death as a result of poisoning. Object: This report was designed to investigate the epidemiology and incidence of CO poisoning in Mazandaran province from 2016 to 2018. Methods: This is a descriptive-analytical and retrospective review of the evidence gathered from the files of the deceased individuals who died as a result of CO poisoning in Mazandaran province's forensic medicine department from 2016 to 2018. Results: 83 deaths due to CO poisoning were reported in this study. All deaths were due to city gas poisoning, and 56% of these poisonings were related to group death. Conclusion: CO poisoning is still a significant public health issue. The most common source of CO poisoning is city gas. Raising the concern of the individuals can reduce the number of Co poisoning cases in the Mazandaran.

Source link: https://doaj.org/article/5d03968fd36042b3a905a9319466b9dc

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions