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Carbon Dioxide - ClinicalTrials.gov

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Last Updated: 10 August 2022

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Arterial and End-Tidal CO2 Gradient as a Mortality Predictor in Critical Care Patients

The patient's mechanical ventilation settings can be controlled by determining the Partial Arterial Carbondioxide concentration in the patient's blood gas result. In healthy people, the difference between the paCO2 value in the blood gas and the End-tidal Carbon dioxide value determined in the mechanical ventilator is 3-5mmHg, while in critical care patients, this difference is even greater. In cases where mortality is high, such as global perfusion disorder, shock disorders, and severe pulmonary embolism, among other things, there is a larger increase in the difference between paCO2 and ETCO2 in critically ill patients in the intensive care unit. It was planned to study the difference between the paCO2 value in the blood gas samples from the patient and the ETCO2 value calculated in the mechanical ventilator to determine the patient's mortality rate.

Source link: https://clinicaltrials.gov/ct2/show/NCT05341258


A Multicentre, Randomized-controlled Trial of EXtracorporeal CO2 Removal to Facilitate Early Extubation Compared to Invasive Mechanical Ventilation in Patients With Severe Acute Exacerbation of COPD (X-COPD)

The new report establishes a link between veno-venous extracorporeal carbon dioxide removal in a severe acute respiratory exacerbation of COPD, which necessitates prompt extubation in terms of reducing mortality or severe disability in terms of reducing mortality or severe disability. The study found that avoiding IMV could reduce mortality and greatly improve quality of life, particularly in terms of avoiding the occurrence of tracheostomy and long-term home IMV. Patients with acute exacerbation of severe COPD, necing extensive mechanical ventilation, will be treated either with traditional care or VV-ECCO2R to promote early extubation.

Source link: https://clinicaltrials.gov/ct2/show/NCT03584295

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions