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Carbon-13 Magnetic Resonance - DOAJ

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Last Updated: 02 November 2021

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Monitoring Early Glycolytic Flux Alterations Following Radiotherapy in Cancer and Immune Cells: Hyperpolarized Carbon-13 Magnetic Resonance Imaging Study

A new imaging method-- named dynamic nuclear polarization carbon-13 magnetic resonance imaging-- probes the glycolytic change in a real-time, dynamic manner. Complying with irradiation, the pyruvate-to-lactate conversion rates on DNP 13 C-MRI were substantially reduced in the hmc3 and the fadu cells but increased in the THP-1 cells. Western blot analysis validated the similar patterns in LDHA and LDHB expression levels.

Source link: https://doi.org/10.3390/metabo11080518

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions