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Carbohydrate Fat - Europe PMC

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Last Updated: 05 August 2022

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Preoperative Short-term High-Carbohydrate Diet Provides More High-Quality Transplantable Fat and Improves the Outcome of Fat Grafts in Mice.

Background Patients with a low BMI may have abnormally high-quality adipose tissue for transplantation. Aims The authors investigated inguinal fat pad swap in mice fed on a short-fat diet or a high-carbohydrate diet preoperatively, as well as post- transplantation morphological and histological differences. Following hematoxylin and eosin staining, as well as CD34 and proliferating cell nuclear immunostaining, histological investigations were carried out. Using quantitative polymerase chain reaction, the Vascular endothelial growth factor-u03b1 and platelet-derived growth factor-u03b1 were determined. The HFD and HCD groups' inguinal fat pad volume increased. HCD grafts had improved volume retention and reduced oil cyst formation, perhaps due to better angiogenesis and adipogenesis. HCD enlarged adipose tissue and increased graft survival rates, which may have been due to fat browning and increased angiogenesis after grafting.

Source link: https://europepmc.org/article/MED/35460566


Dietary Carbohydrate as Glycemic Load, Not Fat, Coupled with Genetic Permissiveness Favoring Rapid Growth and Extra Calories, Dictate Metabolic Syndrome and Diabetes Induction in Nile Rats ( Arvicanthis niloticus ).

Objective Whether dietary carbohydrate or fat is more important in type 2 diabetes induction uncomplicated by dietary fiber was addressed in a spontaneous diabetic model, the diurnal Nile rat that mimics human disease. Methods 138 male Nile rats were fed plant-based and animal-based saturated fat where 10% electricity as CHO and fat were exchanged over five diets, retaining protein constant, from 70:20 to 20:60:20 as CHO: protein:protein %energy. Diabetes induction was investigated by: 1. diet composition, i. e. , CHO:fat ratio, to study diet; 2. quintiles of average caloric intake per day to investigate the effects of calories; and 3. quintiles of diabetes severity were used to investigate epigenetic effects on diabetes resistance. The GLoad was > 175/2000 kcal/day and the diet provided > 57% as CHO.

Source link: https://europepmc.org/article/MED/35893924


High-Fat or High-Carbohydrate Meal-Does It Affect the Metabolism of Men with Excess Body Weight?

The aim of this study was to investigate the effects of a standardized high-fat meal in men with varying nutritional status, as well as changes in energy expenditures and changes in the oxidation of energy substrates, as well as the presence of glucose, insulin, triglycerides, and homocysteine in blood serum in relation to a standardized high-carbohydrate meal in men with varying nutritional status. Following a high-fat or high-carbohydrate meal, men with elevated body weight metabolized the key nutrients differently than men with normal body mass, and postprandial insulin secretion was also different.

Source link: https://europepmc.org/article/MED/35889836


Associations of lower-carbohydrate and lower-fat diets with mortality among people with prediabetes.

National Death Index mortality results were correlated to Mortality status until 31 December, 2015. Conclusions Achievable and healthy LCD scores were correlated with improved blood glucose, insulin, C-reactive protein, and blood lipids, according to the study, although a poorer LFD score was associated with lower blood glucose and CRP at baseline. Healthy LCD score, 0. 85 for unhealthy LCD score, 1. 11 for poor LFD score, and 1. 11 for unhealthy LFD score were 0. 88 for unhealthy LFD score, respectively. With a 14%-37% reduced all-cause mortality, Isocalorically replacing 3%-5% of low-quality carbohydrate or saturated fat with high-quality carbohydrate, plant-based protein, or unsaturated fat was shown to a reduced all-cause mortality. Conclusions: Healthy LCD and LFD scores were often associated with lower all-cause mortality, but poor LCD and LFD scores were also correlated with elevated all-cause mortality in people with prediabetes, according to experts with prediabetes.

Source link: https://europepmc.org/article/MED/35421220


Brown adipose tissue–associated postprandial thermogenesis in humans: Different effects of isocaloric meals rich in carbohydrate, fat, and protein

The rise in whole-body energy expenditure following a single meal ingestion, also known as diet-induced thermogenesis, varies greatly depending on the meal's macronutrient content. After eating a carbohydrate-, protein-, or fat-rich meal, we examined the effects of meal composition on BAT-associated DIT in humans, healthy male participants underwent [18 F]fluorodeoxyglucose-based DIT to measure BAT generation, and respiratory gas analysis for two hours after ingestion. In the group with high-BAT activity, the DIT after C-meal ingestion correlated positively with BAT survival, and was nearly twice higher in the group with high-BAT levels than in the group with low-BAT activity.

Source link: https://europepmc.org/article/PPR/PPR512665


Acute effects of prior dietary fat ingestion on postprandial metabolic responses to protein and carbohydrate co-ingestion in overweight and obese men: A randomised crossover trial.

Omega-3 polyunsaturated fatty acids may be able to shield insulin resistance from the deleterious effects of saturated fatty acids on insulin resistance. However, the relationship between SFA and n-3 PUFA is not well investigated, and excess fat consumption contributes to anabolic and insulin resistance as well as anabolic and insulin resistance. Methods Eight middle-aged males with overweight or obesity ingested either an SFA, or isoenergetic SFA and FO emulsion emulsion, or water/control, 4 h before a bolus of milk protein and dextrose. Result During Lipid Ingestion Intake of protein and dextrose, early postprandial uptake of branched chain amino acids into the skeletal muscle, and attenuated the peak glycaemic response, but not accompanied by differences in whole body or peripheral insulin sensitivity between visits. While an increase in SFA and FO, relative to Con, muscle uptake of free fatty acids was unaffected, according to Con.

Source link: https://europepmc.org/article/MED/35764009


Restricted Carbohydrate Diets High in Fat Are Associated with Increased Likelihood of Prevalent Metabolic Syndrome

Results Compared to those who followed all AMDR macronutrient recommendations, the chances of experiencing metabolic syndrome were 1. 085 times higher among those that followed a restricted carbohydrate diet and 1. 115 times higher for those that followed only current recommendations for total carbohydrates. Regardless of class, higher fat intake was correlated with an increased risk of metabolic syndrome among people on restricted carbohydrate diets but not among those who adhered to new carbohydrate recommendations. Conclusions The likelihood of common metabolic syndrome was moderately higher among people who consumed restricted carbohydrate diets relative to those who followed all macronutrient recommendations. IAFNS is a nonprofit science group that pooles funds from industry collaborators and advances science through in-kind and financial contributions from public and private sector participants.

Source link: https://europepmc.org/article/MED/PMC9214251


Replacing Saturated Fat With Unsaturated Fat or Carbohydrate Does Not Affect Lp(a): A Secondary Data Analysis of Two Randomized Controlled Trials

Abstract Summary of Objectives Lipoprotein [Lp] is a risk factor for atherosclerotic cardiovascular disease in a novel way. However, some studies have shown increased Lp following diets low in saturated fatty acids. Both trials involved a 2-wk run-in diet [Fat: 34%; CHO: 51%; Protein: 16%] followed by three diets in which 5-6% of SFA was lost, with proportionate rises in MUFA, PUFA, or CHO; protein remained stable; protein remained stable; protein: unchanged. In total, six SFA displacement scenarios were evaluated. Comparing between-diet and placebo studies showed no effect of SFA reduction when the replacement nutrient was MUFA, PUFA, orCHO. Conclusions 56% of SFA with MUFA, PUFA, or Cho was not affected by it after 5-6-wks in adults at risk of ASCVD with low baseline Lp. These results do not correspond to the earlier observed increases in Lp with low SFA diets.

Source link: https://europepmc.org/article/MED/PMC9193633


Low-Carbohydrate Diets, but Not Low-Fat Diets, Increase Nonalcoholic Fatty Liver Disease Risk in the Framingham Heart Study

Abstract Objectives: Nonalcoholic fatty liver disease is a common disease that is associated with morbidity and mortality. Weight loss is primarily concerned with weight loss, but no research on the long-term effects of low-fat diets or low-carbohydrate diets, two common weight loss methods, are available; however, research on the long-term effects of low-fat diets or low-carbohydrate diets, two common weight loss methods, are not known; however, no studies on obesity prevention are available; however, research on weight loss or low-carbohydrate diets, which are focuses on NAFLD risk In a U. S. community setting, we investigated the possibility of LFD and LCD interacting with NAFLD risk. Methods We included participants from the Framingham Heart Study's second and third cohorts. Liver fat was measured using the average liver fat attenuation referenced to a radiopaque phantom to determine the liver phantom ratio at baseline and after six years. Many with higher LFD scores had the same dietary profile, though protein intake was similar. Conclusions: In our study, higher adherence to LCD is correlated with an elevated risk of incident NAFLD among women.

Source link: https://europepmc.org/article/MED/PMC9194076


Objective ambulatory pH monitoring and subjective symptom assessment of gastroesophageal reflux disease show type of carbohydrate and type of fat matter.

Background: Background The increased incidence of gastroesophageal reflux disease in U. S. veterans is coincident with increased excess body mass. Methods Ninety-eight veterans with obesity/obesity, and empiric proton pump inhibitor therapy were among the Tennessee Valley Healthcare System's ninety-eight veterans who were overweight/obesity, as well as empiric proton pump inhibitor therapy. Subjective signs were assessed using the Gastroesophageal Reflux Disease Questionnaire and Symptom Assessment Scale. Pathologic GERD or inconclusive GERD have been characterized as either pathologic GERD or inconclusive GERD. More AET is a result of a higher intake of sugar-sweetened beverages, which has been correlated with higher AET. Higher saturated-to-unsaturated fat intake is correlated with a rise AET and number of reflux episodes. More heartburn, regurgitation, acid taste, and nausea severity were all present in pathologic GERD patients. Conclusion Of the numerous foods and nutrients tested, the type of carbohydrate, and the type of fat consumed with objective and/or subjective GERD testing were among the many foods and nutrients tested.

Source link: https://europepmc.org/article/MED/35663436

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions