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Patients with a low BMI may have inadequate high-quality adipose tissue for transplantation. Objectives After transplantation: The authors investigated inguinal fat pad alternation in mice fed on a short-time high-fat diet or a high-carbohydrate diet preoperatively, as well as the morphological and histological differences after transplantation. Mice were fed HFD, HCD, or regular diets for 2 to 4 weeks. Using quantitative polymerase chain reaction, the Vascular endothelial growth factor-u03b1 and platelet-derived growth factor-u03b1 were determined. In the HFD and HCD groups, the inguinal fat pad volume increased. HCD grafts had improved volume retention and reduced oil cyst formation, possibly due to improved angiogenesis and adipogenesis. HCD produced increased adipose tissue and elevated graft survival rates after transplantation, which may be due to fat browning that occurred before grafting and enhanced angiogenesis after grafting.
Source link: https://doi.org/10.1093/asj/sjac105
Ex vivo test of the hypothesis that a high-carbohydrate diet reduces the oxygen flux of adipocyte mitochondria. Participants in a randomized-controlled weight loss maintenance feeding trial found lower rates of maximal adipose tissue mitochondrial respiration in individuals eating a high-carbohydrate diet or a low-carbohydrate diet between ten to 15 weeks than those who followed a moderate-carbohydrate diet or a low-carbohydrate diet from ten to ten weeks than those who were on a moderate-carbohydrate diet or a low-carbo.
Source link: https://doi.org/10.1038/s41430-022-01097-3
The effects of carbohydrates on body weight and insulin sensitivity are mixed. We investigated the effects of a low-fat, plant-based diet on body weight, body composition, and insulin resistance in this 16-week random controlled clinical trial. Insulin resistance was measured using the Homeostasis Model Assessment index. To determine the relationship between carbohydrate intake, body composition, and insulin resistance, a linear regression model was used. Changes in carbohydrate intake as a percentage of energy, fat mass, volume of visceral fat, and HOMA are all negatively correlated with changes in BMI, fat mass, percentage of energy consumption, and HOMA. Changes in BMI, fat mass, and volume of visceral fat decreased in tandem with decreases in visceral fat indices. And after adjusting for energy intake, the correlations between total and insoluble fiber and changes in BMI and fat mass remained strong.
Source link: https://doi.org/10.3390/nu10091302
Endurance athletes often use nutrient-based diets to increase endurance. Although professional experts recommend high carbohydrate diets to optimize fitness, several athletes, and researchers have recently developed an interest in the ketogenic diet in the hopes of promoting u201cfat conversion, which would allow athletes to tap into the virtually infinite energy sources from stored body fat. The present review investigated the effects of participants' hydra, HC, and KD on endurance in a 30-kilometer realistic cycling time trial, physiological responses during the TT, and muscle session fuel percentile before and after the TT using ultrasonic imaging. Compared with HD and lower following the TT, KD was lower during KD and lower following the TT, relative to fasted resting values under all conditions. In this population, further research is required to determine the effects of HC and KD on TT results.
Source link: https://doi.org/10.51224/cik.2022.42
The aim of this case study was to publish the findings and subjective evaluations of a long-distance triathlete who was suffering from gastrointestinal distress in the Ironman competition. For 32 weeks, the lacto-ovo vegetarian convertion converted his usual high carbohydrate intake diet to a LCHF diet. While on the LCHF diet, he competed in three professional races, but as instructed, he quickly restored CHO intake in the preevent meals and during the run. This long-term LCHF intervention did not solve the athlete's digestive problems, it was linked to poor results in both the half-Ironman and Ironman tournaments, and it had a negative effect on the athlete's subjective well-being, in conclusion.
Source link: https://doi.org/10.1123/ijsnem.2018-0124
Background The Scientific Advisory Committee on Nutrition released a risk report on lower carbohydrate intakes for adults with type 2 diabetes in May 2021. The purpose of the study was to review the data on u2018low-carbohydrate diets in comparison to the new UK government guidance on adult T2D adults with T2D. SACN's remit is to investigate the risks and benefits of nutrients, dietary patterns, food or food components for health by examining scientific results and making dietary recommendations for the UK based on the company's findings. The WG included members of SACN and members nominated by Diabetes UK, the British Dietetic Association, Royal College of Physicians, and Royal College of General Practitioners. Representatives from NHS England and NHS Health Improvement, the National Institute for Health and Care Excellence, and devolved health departments were also invited to attend the WG.
Source link: https://doi.org/10.1017/s0007114521002373
In the LCD group mice, however, muscle mass and grip strength decreased relative to those in the control group, while the number of SGLT2i group mice increased. In the LCD group, the amino acid content in the liver, skeletal muscle, and serum were lower than those in the Ctrl group, but it was higher in the SGLT2i group mice. In the LCD group mice, short-chain fatty acids in rectal feces were lower than those in the Ctrl group, although they were higher in the SGLT2i group mice.
Source link: https://doi.org/10.3390/nu14173531
One potential treatment is vaping nerve stimulation, which stimulates the sensory afferents innervating the stomach that promote stomach volume and establish satiety. However, new VNS strategies and stimulus optimization could be aided by additional knowledge of the underlying neural response to stomach distension. Obesity-prone Sprague Dawley rats followed a strict, high-carbohydrate, or high-fat diet for several months, contributing to diet-induced obesity in the two groups. Distension's tone during distension was similar to baseline tone prior to distension.
Source link: https://doi.org/10.1038/s41598-021-89465-0
Type 2 diabetes mellitus is getting more common, and Low-Carbohydrate Diets are on the rise. However, there is a need to determine people with T2DMu2019s LCD display, their motivations for participating in such a diet, how they maintain it, and any challenges they face. Within a sample of people with T2DM, this research sought to assess the effect of adhering to a LCD. Ten participants with T2DM were recruited using a self-selecting sampling procedure from an online diabetes group that promotes LCDs. Participants reported increasing their C apability to use LCDs, and M otivation to monitor diabetes outcomes affected adherence, but M otivation to monitor diabetes outcomes influenced adherence. However, problems were reported with the O pportunity to engage in behaviour, largely influenced by social support. Health professionals and others may be able to gain knowledge, understanding, and assistance in sustaining a LCD long-term.
Source link: https://doi.org/10.1371/journal.pone.0273422
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