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One potential therapy is vaping nerve stimulation, which stimulates the sensory afferents innervating the stomach that release stomach volume and establish satiety. However, new VNS strategies and stimulus optimization may benefit from additional insight into stomach distension's underlying neural response. Obesity-prone Sprague Dawley rats adhered to a strict, high-carbohydrate, or high-fat diet for several months, contributing to diet-induced obesity in the latter two groups. The tone during distension was compared to baseline tone prior to distension, and during tension was compared to baseline tone during distension.
Source link: https://doi.org/10.1038/s41598-021-89465-0
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