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Carbapenem-resistant Enterobacteriaceae - Springer Nature

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Last Updated: 02 May 2022

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Detection of intestinal colonization by carbapenem-resistant Enterobacteriaceae (CRE) among patients admitted to a tertiary care hospital in Egypt

This research was designed to determine the prevalence of CRE intestinal disease among admitted patients in a tertiary care hospital in Egypt's admitted patients in order to determine carbapene-producing genes and identify potential risk factors of CRE colonization. Patients within 48 hours of hospital admission were enrolled with one hundred rectal swabs. Rapidec Carbapenemase production was confirmed by a rapid NP test and multiplex PCR for bla _OXA-48-like, bla _VIM-like, bla _VIM-like, bla _IMP-like, bla _VIM-like, bla _IMP-like, bla _IMP-like, and bla _KPC-like, bla _M-like, _KPC-like, –like, a production was also X NP-like, PCR for _W-like, _Se, _N _C-like, _A-like, _N-like, _Se _like, _IM-like, _LIM-like, _C-like, _IM-like, _VIM-like, _IM-like, _KPC-like, CRE colonization was at 28 percent in those countries. Rapidec Carba NP had promising results in 29/36 CRE isolates, although seven isolates failed; six of them harbored bla _OXA-48-like. Conclusions Our findings show that CRE colonization is disseminating in our healthcare facility, a development that should be considered as potential pathogens for infections in high risk patients.

Source link: https://doi.org/10.1186/s43042-022-00295-9


Necrotizing fasciitis of the vulva due to carbapenem-resistant Enterobacteriaceae as a complication of acute myeloid leukemia treatment: a case report

Presentation of a Case We present the case of a Caucasian 52-year-old Caucasian woman with acute myeloid leukemia who was admitted to an inpatient hematology unit at a university referral hospital in Portugal. Following first line chemotherapy in the context of deep medullary aplasia, the patient developed a localized septic fasciitis that progressed to a necrotizing fasciitis. In both vulvar exudate and blood cultures, Klebsiella was isolated. The hematologic disease's reevaluation of the hematologic disease showed no response to the first cycle of induction therapy. Endemic dissemination of carbapenem-resistant Enterobacteriaceae is a reality, and health services must be implemented urgently to reduce morbidity and mortality due to health facility-related infections.

Source link: https://doi.org/10.1186/s13256-021-03179-5

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions