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Last Updated: 02 October 2022

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A collagen-based sealant to prevent in vivo reformation of epidural scar adhesions in an adult rat laminectomy model

In an adult rat model of laminectomy, the authors investigated the use of a collagen-based sealant, Gel Amidon Oxydu00e9, in preventing the formation of epidural scar adhesions. Rats in Thirty-two adults in Sprague gowley underwent a complete L5u20136 laminectomy, after which the dura mater was revealed and the left adjacent L-4 and L-5 nerve roots were revealed. Magnetic resonance imaging revealed that important epidural adhesions were present in the control rats but not in the experimental rats, three months after reoperation. The experimental rats' peridural space was also larger than in the controls, according to histological analysis. In vivo, the authors found that GAO may be a safe and effective antiscarring adhesion biomaterial. When integrated into the laminectomy site, GAO may be able to avoid the onset and propagation of epidural scar adhesions in humans.

Source link: https://doi.org/10.3171/spi.2002.97.1.0069


Pit and Fissure Sealant versus Fluoride Varnish for the Prevention of Dental Caries in School Children: A Systematic Review and Meta-Analysis

Due to the rise in caries prevalence amongst children, children's dental health has been the biggest concern. Effective dental caries prevention measures include pit and fissure sealant and fluoride varnish. The objective of this systematic review with meta-analysis was to compare pit and fissure sealants with fluoride varnish for caries prevention of first permanent molars among schoolchildren. In both groups, a total number of four research was included, with a total of 1249 children in both groups. As for the lowering of DMFS increment, the study showed no statistical difference between FV and PFS in terms of decreasing DMFS increments. At a 2 year-u2019 follow-up, the findings showed there is no significant difference between PFS and FV in caries prevention effectiveness, ensuring the use of FV is more cost-effective and easier to apply.

Source link: https://doi.org/10.1155/2022/8635254


Glass Ionomer Cement as a preventative fissure sealant for first permanent molars in high caries risk patients waiting general anaesthetic—a case series

Purpose/aim of this case series was to determine the continued suitability of Glass Ionomer Cement Fissure Sealants for use in paediatric patients. Harrogate and District NHS Foundation Trust Community Dental Service found instances where GIC Fissure Sealants were used in paediatric patients awaiting exodontia general anaesthetic. Conclusions The results revealed promising results for GIC fissure sealants, with an average retention of 77% u2013 in accordance with the wider literature's findings on GIC fissure sealants.

Source link: https://doi.org/10.1038/s41405-022-00119-3


Dental caries prediction and the indication of pit and fissure sealant in children first permanent molars: a prospective study

Methods: This 7-year cohort study began in 2010 with a sample of 639 children from Southern Brazil. At baseline and used to determine dental caries risk, maternal education, family income, parental opinion on child oral hygiene, and severe dental caries were all collected. In correctly identifying sound children who would not need to be concerned with pit and fissure sealant, poor family income and poor parental opinion of child oral health were moderately helpful. However, all of the approved criteria incorrectly identifying children who later developed dental caries in first permanent molars. Our findings support the belief that investing in dental caries prevention that takes into account common risk factors.

Source link: https://doi.org/10.21203/rs.3.rs-1781462/v1


Caries-Preventive Effect of Fissure Sealant Containing Surface Reaction-Type Pre-reacted Glass Ionomer Filler and Bonded by Self-etching Primer

Objective: We wanted to see the caries-prevention effectiveness of a pre-reacted glass ionomer filler and bonded by self-etching primer against two standard resin-based sealants bonding by acid etching in terms of enamel deposition and remineralization, enamel bond strength, and debonded enamel surfaces. Demineralization, remineralization, and bond strength of untreated enamel and enamel incisors were assessed among the sealants by polarizing microscopy and microradiography, while bond strength was determined by scanning electron microscopy.

Source link: https://doi.org/10.17796/jcpd.36.4.n444r730r773un53


Occlusal caries formation in vitro: comparison of resinmodified glass ionomer with fluoride-releasing sealant

Prophylaxis was carried out on occlusal surfaces of 12 caries-free mandibular molar teeth that had not been exposed to the oral cavity but not exposed to fluoride-free prophylaxis. An experimental light-cured resin-modified glass ionomer sealant was applied to mesial tooth halves' occlusal surfaces, and for comparison, a light-cured fluoride-releasing pit and fissure sealant was applied to the occlusal surfaces of the corresponding distal tooth halves' occlusal teeth halves' occlusal tooth halves' occlusal teeth halves' occlusal surfaces. Occlusal lesions were ended at the point where bonding between the occlusal enamel and RMG or PFS was broken. Both RMG and PFS showed adequate adaptation of the materials with obliteration of the typical pit and fissure surface morphology. Both the resin-modified glass ionomer and fluoride-releasing sealant glass shielde enamel coated the pit and fissure enamel from caries development, but the resin-modified glass ionomer reduced the degree of caries participation in the adjacent unidentified occlusal incline enamel when compared to the resin sealant.

Source link: https://doi.org/10.17796/jcpd.24.4.hv752511776h5001


Effect of Silver Nanoparticle-Added Pit and Fissure Sealant in the Prevention of Dental Caries in Children

Objective: The aim of this research was to determine the effects of pit and fissure sealant mixed with silver nanoparticles on dental caries by means of monthly measurement of fluorescence with DIAGNOdent for over six months. The first molars, who were healthy, were investigated by a split-mouth investigation on 40 children aged 6-10 years old with healthy, erupted permanent first molars. In comparison to the conventional group, a three-fold reduction in fluorescence was observed in the silver nanoparticles group. Conclusions: The silver nanoparticle-mixed sealant reduced tooth demineralization and most likely increased remineralization, as compared to the conventional sealant.

Source link: https://doi.org/10.17796/1053-4628-41.1.48


Evaluation of Solubility and Microleakage of Glass Carbomer Sealant

For seven days, 20 glass carbomer and conventional glass ionomer specimens were collected and immersed in artificial saliva of pH 4 and 6 for a seven days, according to study concept: For evaluation of solubility, 20 glass carbomer and traditional glass ionomer specimens were collected and immersed in artificial saliva of pH 4 and 6 were prepared and immersed in artificial saliva of pH 4 and 6. Glass carbomer was compared to a conventional resin sealant for evaluation of microleakage. At both pH levels, the glass carbomer specimens were less soluble than the conventional glass ionomer. Glass carbomer can be used as an alternative fissure sealant product, particularly in young children with partially erupted teeth and where moisture control is difficult.

Source link: https://doi.org/10.17796/1053-4628-39.5.429

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions