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Last Updated: 15 January 2023

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A collagen-based sealant to prevent in vivo reformation of epidural scar adhesions in an adult rat laminectomy model

In an adult rat model of laminectomy, the authors investigated the effects of a collagen-based sealant, Gel Amidon Oxyd U00e9, in preventing epidural scar adhesion formation in an epidural scar tissue model. The dura mater was exposed and the left adjacent L-4 and L-5 nerve roots were revealed after a complete L5–u20136 laminectomy was performed in which the adult Sprague u2013Dawley rats underwent a complete L5u20136 laminectomy was performed, and the left side L-4 and L-5 nerve roots were revealed. Magnetic resonance imaging revealed that important epidural adhesions were present in the control rats but not in the experimental rats three months after reoperation. The experimental rats' peridural space was also larger than that in the controls, according to histological analysis of the laminectomy site. In vivo, the authors discovered that GAO may be a safe and effective antiscarring adhesion biomaterial. When integrated into the laminectomy site, GAO may be able to prevent the onset and establishment of epidural scar adhesions in humans.

Source link: https://doi.org/10.3171/spi.2002.97.1.0069


Comparison between Fissure Sealant and Fluoride Varnish on Caries Prevention for First Permanent Molars: a Systematic Review and Meta-analysis

Based on two new systematic reviews, current recommendations recommend a preference for fissure sealant over fluoride varnish. This systematic review and meta-analysis was conducted in order to more accurately evaluate the clinical results of FS and FV on caries prevention for FPMs. At the second-generation follow-up, we found no statistical difference on caries incidence or occlusal DMFS rise between sealant group and fluoride varnish group, according to our meta-analysis for the first time. In that sense, biannual FV or FS applications can be equally effective on FPMs prevention.

Source link: https://doi.org/10.1038/s41598-020-59564-5


Pit and Fissure Sealant versus Fluoride Varnish for the Prevention of Dental Caries in School Children: A Systematic Review and Meta-Analysis

Due to the rise in caries prevalence amongst children, children's dental health has been the biggest worry. Dental caries can be prevented by pit and fissure sealant and fluoride varnish. The aim of this systematic review with meta-analysis was to compare pit and fissure sealants with fluoride varnish for caries prevention of first permanent molars among schoolchildren. This is a meta-Analysis, which involves random control trials that compare the results of PFS with FV within 24 months of follow-up. In terms of decreasing DMFS increment, the report showed no statistical differences between FV and PFS in terms of decreasing DMFS increment. At the 2nd year of this meta-analysis, there is no significant difference between PFS and FV in caries prevention effectiveness, a strong recommendation for FPMs, despite the fact that it is more affordable and easy to use.

Source link: https://doi.org/10.1155/2022/8635254


Glass Ionomer Cement as a preventative fissure sealant for first permanent molars in high caries risk patients waiting general anaesthetic—a case series

The aim of this case series was to determine the Glass Ionomer Cement Fissure Sealants' continuing use in paediatric patients. Objective/aim Within the Harrogate and District NHS Foundation Trust Community Dental Service, a retrospective clinical review was carried out to determine situations where GIC Fissure Sealants were used in paediatric patients awaiting exodontia general anaesthetic. Conclusions The findings reported encouraging results of GIC fissure sealants, with an average retention of 77% u2013, which was in accordance with the wider literature results for GIC fissure sealants.

Source link: https://doi.org/10.1038/s41405-022-00119-3


Dental caries prediction and the indication of pit and fissure sealant in children first permanent molars: a prospective study

Methods: This 7-year cohort survey began in 2010 with a sample of 639 children from Southern Brazil. At baseline, dental caries prevalence was determined, as well as parental knowledge, family income, parent opinions on child oral hygiene, and severe dental caries experience. Low family income and poor parental perception of child oral health were moderately helpful in correctly identifying sound children who did not need to have pit and fissure sealant. However, all of the tested criteria have lower reliability, identifying children who later developed dental caries in first permanent molars. The results of our research support the belief that investing in programs that take into account common risk factors is still the most effective option for dental caries prevention.

Source link: https://doi.org/10.21203/rs.3.rs-1781462/v1


Caries-Preventive Effect of Fissure Sealant Containing Surface Reaction-Type Pre-reacted Glass Ionomer Filler and Bonded by Self-etching Primer

Object: We wanted to determine the caries-preventive effect of a pre-reacted glass ionomer filler and bonded by self-etching primer versus two conventional resin-based sealants bonded by acid etching in terms of enamel degradation and remineralization, enamel bond strength, and integrity of debonded enamel surfaces. Conclusions: An S-PRG filler-containing fissure sealant, bonded by self-etching primer, will eliminate enamel demineralization, microleakage, and gaps between the tags created by acid etching, regardless of the enamel condition.

Source link: https://doi.org/10.17796/jcpd.36.4.n444r730r773un53


Occlusal caries formation in vitro: comparison of resinmodified glass ionomer with fluoride-releasing sealant

Prophylaxis was carried out on occlusal surfaces of 12 caries-free mandibular molar teeth that had not been previously exposed to the oral cavity and had not been exposed to fluoride-free prophylaxis. The corresponding distal tooth halves' occlusal surfaces were prepared for an experimental light-cured resin-modified glass ionomer sealant, with a light-cured fluoride-releasing pit and fissure sealant on the occlusal surfaces of the corresponding distal tooth halves. Occlusal lesions came to a halt at the point where bonding between the occlusal enamel and RMG or PFS was breached. Both RMG and PFS tested the materials with satisfactory adaptation of the usual pit and fissure surface morphology. The resin-modified glass ionomer and fluoride-releasing sealant coating coated the pit and fissure enamel from caries development, but the resin-modified glass ionomer reduced the extent of caries involvement in the nearby unsealed occlusal incline enamel when compared to the resin sealant.

Source link: https://doi.org/10.17796/jcpd.24.4.hv752511776h5001


Effect of Silver Nanoparticle-Added Pit and Fissure Sealant in the Prevention of Dental Caries in Children

Objective: The aim of this research was to determine the effects of pit and fissure sealant mixed with silver nanoparticles on dental caries by using monthly measurements of fluorescence with DIAGNOdent over six months. Conclusions: Conventional sealant had an average microleakage of 30. 6%, and the silver nanoparticle-mixed sealant had 33. 6%. In the silver nanoparticles group, there was a three times higher reduction in fluorescence relative to the conventional group. Conclusions: The silver nanoparticle-mixed sealant reduced tooth demineralization and likely increased remineralization, compared to the conventional sealant.

Source link: https://doi.org/10.17796/1053-4628-41.1.48


Evaluation of Solubility and Microleakage of Glass Carbomer Sealant

For seven days, 20 glass carbomer and conventional glass ionomer specimens were collected and immersed in artificial saliva pH 4 and 6 for evaluation. Glass carbomer was compared to a traditional resin sealant for microleakage testing. At both pH values, the glass carbomer specimens were less soluble than the traditional glass ionomer. Glass carbomer is a water repellant that can be used as an alternative fissure sealant product, especially in young children with partially erupted teeth and situations where moisture control is difficult.

Source link: https://doi.org/10.17796/1053-4628-39.5.429


ОNE-YEAR CLINICAL EVALUATION OF THE CARIES-PREVENTIVE EFFECT OF GLASS-IONOMER SEALANT ON NEWLY ERUPTED FIRST PERMANENT MOLARS IN CHILDREN

Background: Dental sealant is a product that is applied to pits and fissures in order to prevent the occurrence of occlusal dental caries. Materials and methods: The study began with 78 healthy, newly erupted first permanent molars, and the second-uptake of the ICDAS II system, medical examination using VistaCam Macro and modified Ryge criteria. We performed a frequency analysis of the data based on the absence or presence of caries after recoding the data obtained from monitoring the newly erupted first permanent molars' occlusal surfaces, we performed a frequency analysis of the results. Results: We found 95% of the examined surfaces healthy using all diagnostic techniques that were used in the group of 5-6-year-olds following the application of glass-ionomer-based sealant in the newly erupted first permanent molars, one year after the sealant's introduction of the sealant.

Source link: https://doi.org/10.5272/jimab.2022282.4418

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions