* If you want to update the article please login/register
Kindler syndrome is a rare form of epidermolysis bullosa, a group of genetic disorders that cause the skin to be extremely fragile and blister quickly. People with Kindler syndrome have skin blisters, particularly on the backs of the hands and the feet's tops, beginning in infancy. The blisters diminish as time goes, but repeated blistering on the hands can cause scarring between the fingers and toes. Affected individuals also have thin, papery skin beginning on the hands and feet and eventually spreading to other areas of the body. Other skin abnormalities associated with Kindler syndrome include patchy skin changes and tiny clusters of blood vessels just under the skin, a form that is also known as poikiloderma. People with Kindler syndrome can also be extremely sensitive to ultraviolet rays from the sun and to sunburn rapidly. Affected individuals are more likely to have severe gum disease, which can lead to tooth loss early in life. The eyelids and the white portion of the eye may be inflamed, if not hydrated, and vision can be affected by damage to the eye's clear outer covering. Squamous cell carcinoma, a form of cancer, raises the risk of getting a Kindler syndrome. Squamous cell carcinoma is most prevalent on the skin, lips, and the inside of the mouth in people with Kindler syndrome.
* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions