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Blood Test - Europe PMC

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Last Updated: 10 August 2022

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Prevalence of G6PD deficiency in Thai blood donors, the characteristics of G6PD deficient blood, and the efficacy of fluorescent spot test to screen for G6PD deficiency in a hospital blood bank setting.

Aims To determine the prevalence of G6PD deficiency in Thai blood donors, the features of G6PD deficiency blood, and the use of a fluorescent spot test to screen for G6PD deficiency in a hospital blood bank setting, investigate G6PD deficiency in a hospital blood bank setting. Methods of collection Blood samples were obtained from 514 Thai blood donors who donated blood at Siriraj Hospital between December 2020 and February 2021. In a hospital blood bank setting, FST was found to be a fast and reliable method for G6PD deficiency screening among Thai blood donors.

Source link: https://europepmc.org/article/MED/35134307


Cost-Effectiveness Analysis of Stockholm 3 Testing Compared to PSA as the Primary Blood Test in the Prostate Cancer Diagnostic Pathway: A Decision Tree Approach.

This paper assessed the cost effectiveness of using Stockholm 3 results in comparison to the prostate-specific antigen test in prostate cancer diagnostic procedures. Methods We developed a decision tree for PSA and STHLM3. The analysis included a Danish hospital perspective with a time frame limited to the prostate cancer diagnostic pathway, beginning with the initial PSA/STHLM3 test and ending with biopsy and histopathological diagnosis. Conclusions STHLM3 testing revealed increased incremental sensitivity, but at higher prices, compared to the PSA test as the initial testing technique in the prostate cancer diagnostic process. The results were highly dependent on the cost of the STHLM3 procedure, so a lower cost of the STHLM3 test would increase its cost efficiency in comparison to PSA tests.

Source link: https://europepmc.org/article/MED/35934771


An investigation of blood, milk, and urine test patterns for the diagnosis of ketosis in dairy cows in early lactation.

The prevalence of ketone bodies in the blood, milk, or urine of dairy cattle is mainly determined by ketone levels. Hyperketonemic cows were tested with BT, MT, and UT for 3 days after being diagnosed with HYK on the day of diagnosis. MT and UT specificity increased from d 0 to d 1, decreased on d 2 and boosted on d 3, and increased on d 3. 5 DIM standardized time to diagnosis ketosis in blood was 5 DIM, moreover, MT and UT had 2 d faster median time to diagnosis ketosis in blood relative to the BT [7 DIM ; and 7 DIM respectively], and UT had 2 d longer median time to ketosis diagnosis in blood. The UT is a more accurate predictor of blood BHB levels than the MT, according to Weir. The UT and MT labs discovered ketotic cows about two d later than the BT, which was about two d later than the BT.

Source link: https://europepmc.org/article/MED/35931489


Impact of a Laboratory-Developed Phenotypic Rapid Susceptibility Test Directly From Positive Blood Cultures on Time to Narrowest Effective Therapy in Patients With Gram-Negative Bacteremia: A Prospective Randomized Trial.

Background Antimicrobial susceptibility testing is often needed before antimicrobial synthesis testing for patients with gram-negative bloodstream infections. Methods This was a prospective, nonblinded, randomized trial comparing the results of a phenotypic rAST technique with conventional AST in hospitalized patients with GN-BSI and source control. In a prespecified subgroup of patients not initially on narrowest therapy and during AS working hours, the distance to narrowest effective therapy was much shorter. Conclusions: rAST did not significantly reduce time to narrowest helpful therapy in patients with GN-BSI, but it did decrease the time to oral antibiotics and length of hospital stay.

Source link: https://europepmc.org/article/MED/35919072


A novel method for extracting circulating cell-free DNA from whole blood samples and its utility in the non-invasive prenatal test.

Method We extracted cfDNA from both plasma and whole blood of the patients' using CEWB and compared it to that extracted using a Qiagen extraction kit, and a droplet digital polymerase chain reaction test was used to determine the fragment size bias. The CEWB group reported lower DNA weight yield than the Qiagen group, according to the Qiagen group. The treatment group extracted by CEWB showed a sensitivity of 100%, a sensitivity of 99. 65%, and a positive predictive value of 95% in a parallel cohort study to assess the effectiveness of the CEWB method in Northern Ireland's Northern Ireland.

Source link: https://europepmc.org/article/MED/35818872

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions