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Blood Test - DOAJ

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Last Updated: 10 August 2022

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Clinical validation of a next-generation sequencing-based multi-cancer early detection "liquid biopsy" blood test in over 1,000 dogs using an independent testing set: The CANcer Detection in Dogs (CANDiD) study.

Multiple-cancer early detection in human medicine is now available in Liquid biopsy kits that interrogate cancer-derived genomic alterations in cell-free DNA in blood, and are now available for veterinary use. The CANcer Detection in Dogs study is a multinational, multi-center scientific research designed to verify the results of a novel multi-cancer early detection liquid biopsy" test in dogs that is used for noninvasive detection and characterization of cancer in dogs based on next-generation sequencing of blood-derived DNA; the study findings are published here. In patients from 30 different cancer types and diseases, the test revealed cancer signals in patients and gave a Cancer Signal Origination prediction for a subset of patients with hematological malignancies. Moreover, the test correctly detected cancer signal in four apparently cancer-free participants before the onset of clinical signs, proving the use of liquid biopsy as an early detection method.

Source link: https://doi.org/10.1371/journal.pone.0266623

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions