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"Abstract Background: The correlation between antihypertensive drug therapy and cancer is equivocal, according to "Abstract Background: The association of antihypertensive drug therapy and cancer is equivocal. Large, rapid rises in blood pressure following HTDT are correlated with increased cancer risk, according to our analysis. Compared to those with no decrease in SBP, SHEP participants taking antihypertensive drugs who resulted in a decrease in seated SBP of 29 mm Hg or more at three months were at a 58% higher risk of cancer-related death during a 15-month follow-up. Participants with maximum seated SBP change in the first three months of therapy had 2. 6-folds higher risk of cancer mortality in comparison to those with the highest seated SBP change occurred at 12 months. IMPACT: Following HTDT, rapid drops in blood pressure may be a risk factor for cancer. ".
Source link: https://doi.org/10.1158/1055-9965.epi-14-0085
Since accounting for asymptomatic prostate-specific antigen testing, and with prostate cancer death, it is uncertain. " Methods: We investigated BP, which was measured at a mean age of 38 years among 430,472 men from five Swedish cohorts, in connection with prostate cancer and prostate cancer deaths. Results: Increasing systolic and diastolic BP levels in combination were directly correlated with a marginally lower prostate cancer risk, with a HR of 0. 98 percent per standard deviation from mid-BP. Higher BP levels per SD of mid-BP were found in those cases, but the connection was limited to distant metastatic disease, and there was no association for BP measured less than ten years ago than diagnosis. Less' symptomatic PSA testing among men with elevated BP levels may explain their reduced risk of prostate cancer. ".
Source link: https://doi.org/10.1158/1055-9965.epi-22-0159
"The use of ambulatory blood pressure monitoring in children and adolescents has dramatically increased since the publication of the last American Heart Association scientific paper on pediatric ambulatory blood pressure monitoring in 2014. This scientific report includes a succinct review of this new study, guidance on the effective use of ambulatory blood pressure monitoring in the clinical setting, and a standardized test framework for the interpretation of ambulatory blood pressure monitoring in children and adolescents.
Source link: https://doi.org/10.1161/hyp.0000000000000215
"Based on a large, real-world, patient-level data set, the global May Measurement Month campaign gives the possibility of determining the risks of universally lowering BP thresholds on the prevalence of hypertension based on a large, real-world, patient-level data set. Methods: After 5 minutes of rest from 4 021 690 standardized, opportunistic BP screenings in several settings of the 2017 to 2019 May Measurement Month campaigns in 104 countries, 104 countries were assessed to determine the socioeconomic and phenotypic effects of three identified BP thresholds. Conclusions: The impact of a universal application of lower BP thresholds for the definition of hypertension would have a huge effect on the prevalence of hypertension in the world, with large disparities between countries and a high degree of ethnic and phenotypic variations, which should be confirmed in dedicated population studies. ".
Source link: https://doi.org/10.1161/hypertensionaha.122.19144
"Background: Previous studies have shown that blood pressure fluctuations and white matter lesions could help determine interactions between blood pressure oscilation and white matter lesions, although the effect of elevated BPV on white matter hyperintensity or cerebral arterial dilation is uncertain. " Measurements for variability of blood pressure were created based on 7 days blood pressure data. Magnetic resonance angiography images were used to determine middle cerebral artery dilation in M1 segment of middle cerebral artery dilation. Both elevated systolic and diastolic BPV were associated with increased WMH volume, as shown by the above tables. In 125 people, MCA dilation was discovered in 125 others. Only in the hypertensive individuals was MCA dilation. WMH increase was discovered to be attributed to dilated MCA. Conclusions: Increasing BPV may be one of the pathophysiological conditions implicating in the small vessel disease independent of hypertension. Increased BPV may play a role in intracranial arterial dilation. Management of BPV may be a way to maintain cerebrovascular stability. ".
Source link: https://doi.org/10.1161/hypertensionaha.122.19269
"Basic components of renin-angiotensin-aldosterone system components in males and females establish the basic sex difference in BP, which may be influenced by birthright planning and the widespread use of BP after birth. " Blood pressure has been found to be similar for both men and women at the age of 70 and older. Understanding the prenatal and sexual dimorphism in BP may help with preventative therapeutic strategies, such as timing and selection of drugs for individuals with abnormal BP. ".
Source link: https://doi.org/10.2174/1573402117666210511011444
"Background: In some patients with coronary artery disease, the normal decrease in systolic blood pressure during workout phase of treadmill exercise does not occur in those with coronary artery disease, but in others with rehabilitation values systolic blood pressure may even exceed peak exercise values. " Objectives: The Treadmill exercise test results revealing the presence and extent of coronary artery disease have traditionally included measures such as exercise duration, blood pressure, and ST-segment reaction to exercise. The three-minute systolic blood pressure ratio is another useful and obtainable measure that can be used in all patients with heart disease screening for suspected ischemic heart disease, and it may raise the sensitivity of exercise tests. The difference between patient with coronary artery disease and those without coronary artery disease was significantly higher in three vessels than in those without coronary artery disease, with a much higher risk of coronary artery disease (SBP/3. 1 minute recovery blood pressure ratio in three vessels than in those without coronary artery disease. 0. 95 vs. 0. 90 vs. "Post exercise blood pressure rises in patients with coronary artery disease is greater than that in patients with normal coronary artery disease" (see figure below).
Source link: https://doi.org/10.47723/kcmj.v12i2.290
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